Evidence map›Paper›PMID 38175912›Full record

ArticleCirculation research2024

Legumain Regulates Regulatory T Cells in Hypertension.

Matthew R Alexander, David G Harrison

Open access · greenAbstract readEditorialComment
In one paragraph

Article in Circulation research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Investigation of the molecular mechanism ofFrontiers in pharmacology · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Matthew R AlexanderDepartment of Medicine, Division of Clinical Pharmacology, and Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN. Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN. Vanderbilt Institute for Infection, Immunology, and Inflammation, Nashville, TN.ORCID 0000-0003-4739-7204
David G HarrisonDepartment of Medicine, Division of Clinical Pharmacology, and Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN. Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN. Vanderbilt Institute for Infection, Immunology, and Inflammation, Nashville, TN.ORCID 0000-0001-9363-6451
Vanderbilt University · US

Funding

Mechanisms of Immune Activation in HypertensionR35HL140016 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HARRISON, DAVID G · 2018 to 2024
$5.3M
Common Inflammation Pathways between Aging and Hypertension That Weaken BoneR01AG076785 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI David G Harrison, Jeffry Stephen Nyman · 2022 to 2026
$2.5M
The Role of CCR10+ Regulatory T Cells In HypertensionK08HL153786 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALEXANDER, MATTHEW R · 2020 to 2024
$792k
BCCMA: Foundational Research to Act Upon and Resist Conditions Unfavorable to Bone (FRACTURE CURB): Role of Hypertension in Favoring OsteoporosisI01BX005866 · VA · VETERANS HEALTH ADMINISTRATION · PI Jeffry Stephen Nyman · 2023 to 2026
–
BLRD VA I01 BX005866NHLBI NIH HHS K08 HL153786NHLBI NIH HHS R35 HL140016NIA NIH HHS R01 AG076785
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HypertensionT-Lymphocytes, RegulatoryAsparaginyl EndopeptidaseCD4-Positive T-LymphocytesHumansTNF Receptor-Associated Factor 6Asparaginyl EndopeptidaseTNF Receptor-Associated Factor 6EditorialshypertensioninflammationT-lymphocytesT lymphocytes, regulatory

Identifiers

PMID38175912
PMCPMC10768802
OpenAlexW4390578115

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.