Evidence map›Paper›PMID 38175599›Full record

ArticleClinical chemistry2024

Screening for Colorectal Cancer: The Role of Clinical Laboratories.

Joseph F Toth, Mehul Trivedi, Samir Gupta

Open access · bronzeAbstract read
In one paragraph

Article in Clinical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Prognostic Value of Long Non-Coding RNAs GUSB Pseudogene 11 in Colorectal Cancer and Its Regulatory Effect on Tumor Progression.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2025
    Article
  2. Review
  3. Liquid Biopsy in the Clinical Management of Cancers.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Joseph F TothDepartment of Internal Medicine, University of California San Diego Health, La Jolla, CA, United States.
Mehul TrivediDepartment of Internal Medicine, University of California San Diego Health, La Jolla, CA, United States.
Samir GuptaDepartment of Internal Medicine, University of California San Diego Health, La Jolla, CA, United States.ORCID 0000-0003-4192-5002
University of California San Diego · US

Funding

VIRAL MALIGNANCYP30CA023100 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DIANE M SIMEONE · 1985 to 2026
$124.9M
CRC-HUB-SPOKE: A ColoRectal Cancer screening Hub for Southern California community health centers.UH3CA233314 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GUPTA, SAMIR, HILL, LINDA L · 2020 to 2023
$4.9M
Post-polypectomy Surveillance for Reducing Colon Cancer Incidence and MortalityR37CA222866 · NCI · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI GUPTA, SAMIR · 2018 to 2023
$3.3M
Surveillance Colonoscopy in Older Adults: The SurvOlderAdults StudyI01HX003605 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI Samir Gupta, Folasade Popoola May · 2023 to 2026
–
HSRD VA I01 HX003605NCI NIH HHS P30 CA023100NCI NIH HHS R37 CA222866NCI NIH HHS UH3 CA233314
6 · The paper itself

Abstract

backgroundColorectal cancer (CRC) is a leading cause of cancer incidence and mortality. Screening can result in reductions in incidence and mortality, but there are many challenges to uptake and follow-up. CONTENT: Here, we will review the changing epidemiology of CRC, including increasing trends for early and later onset CRC; evidence to support current and emerging screening strategies, including noninvasive stool and blood-based tests; key challenges to ensuring uptake and high-quality screening; and the critical role that clinical laboratories can have in supporting health system and public health efforts to reduce the burden of CRC on the population. SUMMARY: Clinical laboratories have the opportunity to play a seminal role in optimizing early detection and prevention of CRC.

Indexed as

Clinical Laboratory ServicesColorectal NeoplasmsBiological TransportEarly Detection of CancerHumansLaboratories, Clinical

Identifiers

PMID38175599
PMCPMC10952004
OpenAlexW4390579176

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.