Evidence map›Paper›PMID 38175586›Full record

ReviewClinical chemistry2024

Circulating Tumor Cells: From Basic to Translational Research.

Luis Enrique Cortés-Hernández, Zahra Eslami-S, Klaus Pantel, Catherine Alix-Panabières

Abstract readReview
In one paragraph

Review in Clinical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Luis Enrique Cortés-HernándezDepartment of Tumor Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID 0000-0003-2743-1524
Zahra Eslami-SEuropean Liquid Biopsy Society (ELBS), Hamburg, Germany.ORCID 0000-0002-3489-2479
Klaus PantelDepartment of Tumor Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Catherine Alix-PanabièresDepartment of Tumor Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID 0000-0002-6401-2903

Funding

Deutsche ForschungsgemeinschaftDeutsche KrebshilfeEuropean UnionFondation ARC pour la Recherche sur le cancerNational Institute of Cancer
6 · The paper itself

Abstract

backgroundMetastasis is the leading cause of cancer-related deaths. Most studies have focused on the primary tumor or on overt metastatic lesions, leaving a significant knowledge gap concerning blood-borne cancer cell dissemination, a major step in the metastatic cascade. Circulating tumor cells (CTCs) in the blood of patients with solid cancer can now be enumerated and investigated at the molecular level, giving unexpected information on the biology of the metastatic cascade. CONTENT: Here, we reviewed recent advances in basic and translational/clinical research on CTCs as key elements in the metastatic cascade. SUMMARY: Findings from translational studies on CTCs have elucidated the complexity of the metastatic process. Fully understanding this process will open new potential avenues for cancer therapeutic and diagnostic strategies to propose precision medicine to all cancer patients.

Indexed as

Neoplastic Cells, CirculatingHumansKnowledgePrecision MedicineTranslational Research, Biomedical

Identifiers

PMID38175586
PMCPMC10765989

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.