Evidence map›Paper›PMID 38175328›Full record

ArticleVeterinary research communications2024

Survey on resistance occurrence for F4

Anna Fratto, Martina Torricelli, Carla Sebastiani, Marcella Ciullo, Andrea Felici, Massimo Biagetti

Abstract read
PubMed Publisher
In one paragraph

Article in Veterinary research communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. The potential of yeast culture for alleviating enterotoxigenicAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2026
    Review
  2. Article
  3. Porcine β-Defensin 2 Expressed inAnimals : an open access journal from MDPI · 2025
    Article
  4. RecombinantApplied and environmental microbiology · 2025
    Article
  5. Selection for Resilience in Livestock Production Systems.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anna FrattoIstituto Zooprofilattico Sperimentale dell'Umbria e delle Marche - Togo Rosati, Via G. Salvemini 1, Perugia, 06126, Italy.ORCID http://orcid.org/0000-0003-1974-9700
Martina TorricelliIstituto Zooprofilattico Sperimentale dell'Umbria e delle Marche - Togo Rosati, Via G. Salvemini 1, Perugia, 06126, Italy. m.torricelli@izsum.it.ORCID http://orcid.org/0000-0001-6409-3582
Carla SebastianiIstituto Zooprofilattico Sperimentale dell'Umbria e delle Marche - Togo Rosati, Via G. Salvemini 1, Perugia, 06126, Italy.ORCID http://orcid.org/0000-0003-3927-3279
Marcella CiulloIstituto Zooprofilattico Sperimentale dell'Umbria e delle Marche - Togo Rosati, Via G. Salvemini 1, Perugia, 06126, Italy.ORCID http://orcid.org/0000-0003-1995-1984
Andrea FeliciIstituto Zooprofilattico Sperimentale dell'Umbria e delle Marche - Togo Rosati, Via G. Salvemini 1, Perugia, 06126, Italy.ORCID http://orcid.org/0000-0002-1306-6629
Massimo BiagettiIstituto Zooprofilattico Sperimentale dell'Umbria e delle Marche - Togo Rosati, Via G. Salvemini 1, Perugia, 06126, Italy.ORCID http://orcid.org/0000-0003-4744-3389

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porcine Post Weaning Diarrhoea (PWD) is one of the most important swine disease worldwide, caused by Enterotoxigenic Escherichia coli (ETEC) strains able to provoke management, welfare and sanitary issues. ETEC is determined by proteinaceous surface appendages. Numerous studies conducted by now in pigs have demonstrated, at the enterocytes level, that, the genes mucin 4 (MUC4) and fucosyltransferase (FUT1), coding for ETEC F4 and F18 receptors respectively, can be carriers of single nucleotide polymorphisms (SNPs) associated with natural resistance/susceptibility to PWD. The latter aspect was investigated in this study, evaluating the SNPs of the MUC4 and FUT1 genes in slaughtered pigs reared for the most in Central Italy. Genomic DNA was extracted from 362 swine diaphragmatic samples and then was subjected to the detection of known polymorphisms on MUC4 and FUT1candidate target genes by PCR-RFLP. Some of the identified SNPs were confirmed by sequencing analysis. Animals carrying the SNPs associated with resistance were 11% and 86% for the FUT1 and MUC4 genes respectively. Therefore, it can be assumed that the investigated animals may be an important resource and reservoir of favorable genetic traits for the breeding of pigs resistant to enterotoxigenic E.coli F4 variant.

Indexed as

Enterotoxigenic Escherichia coliEscherichia coli InfectionsSwine DiseasesAnimalsDiarrheaPolymorphism, Single NucleotideSwineETEC F18ETEC F4FUT 1Marker assisted selection (MAS)MUC 4One healthPost weaning diarrhoea (PWD)Public health

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.