Evidence map›Paper›PMID 38175303›Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2024

Adverse childhood events and mental health problems in cancer survivors: a systematic review.

Chris Hinnen, Emma von Haeseler, Frederiek Tijssens, Floortje Mols

Registry-linked trialOpen access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07481890 (Feasibility and Efficacy of an EMDR Psychotherapeutic Intervention With Additional Procedures), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
13.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07481890 narecruitingnot on this mapstarted 2026, after this paper: background citation

Feasibility and Efficacy of an EMDR Psychotherapeutic Intervention With Additional Procedures (EMDR Toolbox Method) in Improving the Psychological Well-Being of Patients Diagnosed With Oncological Disease: A Randomized Study.

TypeinterventionalSponsorLega Cancro TicinoRan2026 to 2027Enrolled46ConditionsCancer, Psychological DistressArmsSTANDARD EMDR, EMDR TOOLBOX METHOD
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Chris HinnenDepartment of Psycho-Oncology, LUMC Oncology Center, Leiden, the Netherlands. s.c.h.hinnen@lumc.nl.ORCID http://orcid.org/0000-0001-6085-4065
Emma von HaeselerDepartment of Psycho-Oncology, LUMC Oncology Center, Leiden, the Netherlands.
Frederiek TijssensDepartment of Psycho-Oncology, LUMC Oncology Center, Leiden, the Netherlands.
Floortje MolsDepartment of Medical and Clinical Psychology, CoRPS - Center of Research On Psychological Disorders and Somatic Diseases, Tilburg University, Tilburg, the Netherlands.ORCID http://orcid.org/0000-0003-0818-2913
Loyola University Medical Center · USTilburg University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to systematically review the literature on the association between adverse childhood events (ACEs) and mental health problems in cancer survivors.

methodsThis review was conducted in line with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Four databases (PubMed, PsychINFO, Web of Science, and Cochrane) were searched on 27-08-2023.

resultsOf the 1413 references yielded by the literature search, 25 papers met inclusion criteria and were reviewed. Most studies were performed in the USA, most included breast cancer survivors, and the number of included participants ranged between 20 and 1343. ACEs were relatively prevalent, with self-report rates ranging between 40 and 95%. Having been exposed to ACEs was a risk factor for heightened levels of emotional distress, anxiety, depressive symptoms, and fatigue during cancer treatment. Results varied depending on the variables included, and per subscale, but were consistent across different cultures and heterogenous patient groups.

conclusionThe association between ACE and mental health outcomes was significant in most studies. In order to improve treatment for this vulnerable population, it may be necessary to screen for ACEs before cancer treatment and adjust treatment, for example, by means of trauma-informed care (TIC), which recognizes and responds to the impact of trauma on individuals seeking healthcare.

Indexed as

Cancer SurvivorsNeoplasmsAnxietyAnxiety DisordersChildHumansMental HealthSurvivorsAdverse childhood eventsAnxietyCancerDepressionDistressFatigueTrauma-informed care

Identifiers

PMID38175303
PMCPMC10766658
OpenAlexW4390584680

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.