Evidence map›Paper›PMID 38175242›Full record

ReviewApplied microbiology and biotechnology2024

Aspergillus fumigatus escape mechanisms from its harsh survival environments.

Fangyan Liu, Meng Zeng, Xue Zhou, Fujiao Huang, Zhangyong Song

Open access · goldAbstract readReview
In one paragraph

Review in Applied microbiology and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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  11. Efficacy of sodium new houttuyfonate againstFrontiers in pharmacology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Fangyan Liu *School of Basic Medical Sciences, Southwest Medical University, Luzhou, 646000, People's Republic of China.
Meng Zeng *School of Basic Medical Sciences, Southwest Medical University, Luzhou, 646000, People's Republic of China.
Xue ZhouSchool of Basic Medical Sciences, Southwest Medical University, Luzhou, 646000, People's Republic of China.
Fujiao HuangSchool of Basic Medical Sciences, Southwest Medical University, Luzhou, 646000, People's Republic of China.
Zhangyong SongSchool of Basic Medical Sciences, Southwest Medical University, Luzhou, 646000, People's Republic of China. szy83529@163.com.ORCID http://orcid.org/0000-0003-1190-485X
Southwest Medical University · CN

Funding

Department of Science and Technology of Sichuan Province 2022NSFSC1539Department of Science and Technology of Sichuan Province 2022YFS0629Foundation of Southwest Medical University 2022QN042Foundation of Southwest Medical University 2022QN085Foundation of Southwest Medical University 2022QN102Foundation of Southwest Medical University 2022QN118Sichuan Science and Technology Program 2023NSFSC1698Technology Strategic Cooperation Project of Luzhou Municipal People's Government-Southwest Medical University 2018LZNYD-ZK26
6 · The paper itself

Abstract

Aspergillus fumigatus is a ubiquitous pathogenic mold and causes several diseases, including mycotoxicosis, allergic reactions, and systemic diseases (invasive aspergillosis), with high mortality rates. In its ecological niche, the fungus has evolved and mastered many reply strategies to resist and survive against negative threats, including harsh environmental stress and deficiency of essential nutrients from natural environments, immunity responses and drug treatments in host, and competition from symbiotic microorganisms. Hence, treating A. fumigatus infection is a growing challenge. In this review, we summarized A. fumigatus reply strategies and escape mechanisms and clarified the main competitive or symbiotic relationships between A. fumigatus, viruses, bacteria, or fungi in host microecology. Additionally, we discussed the contemporary drug repertoire used to treat A. fumigatus and the latest evidence of potential resistance mechanisms. This review provides valuable knowledge which will stimulate further investigations and clinical applications for treating and preventing A. fumigatus infections. KEY POINTS: • Harsh living environment was a great challenge for A. fumigatus survival. • A. fumigatus has evolved multiple strategies to escape host immune responses. • A. fumigatus withstands antifungal drugs via intrinsic escape mechanisms.

Indexed as

AspergillosisHypersensitivityAntifungal AgentsAspergillus fumigatusEcosystemAntifungal AgentsAspergillosisAspergillus fumigatusDrug resistanceEscape mechanismsImmunity responsesMicroecological agents

Identifiers

PMID38175242
PMCPMC13497423
OpenAlexW4390586795

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.