ArticleAmerican journal of respiratory and critical care medicine2024
Meaningful Endpoints for Idiopathic Pulmonary Fibrosis (IPF) Clinical Trials: Emphasis on 'Feels, Functions, Survives'. Report of a Collaborative Discussion in a Symposium with Direct Engagement from Representatives of Patients, Investigators, the National Institutes of Health, a Patient Advocacy Organization, and a Regulatory Agency.
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Article in American journal of respiratory and critical care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 2 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Normal age-related decline in forced vital capacity: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2026Pooled it
- A systematic review of the role of quantitative CT in the prognostication and disease monitoring of interstitial lung disease.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Improved quality of life, reduced quantitative lung fibrosis in a trial of inhaled pirfenidone for idiopathic pulmonary fibrosis.BMC pulmonary medicine · 2026Trial
- A composite endpoint for systemic sclerosis-associated interstitial lung disease: association with mortality in two clinical trial cohorts.Respiratory research · 2025Trial
- Development and validation of a predictive 6-min walk score in patients with idiopathic pulmonary fibrosis.The European respiratory journal · 2025Trial
- Trial
- Trial
- Zinpentraxin Alfa for Idiopathic Pulmonary Fibrosis: The Randomized Phase III STARSCAPE Trial.American journal of respiratory and critical care medicine · 2024Trial
- Regional micro-computed tomography analysis enables longitudinal detection of compensatory ventilation effects in a mouse model of pulmonary fibrosis.American journal of respiratory cell and molecular biology · 2026Article
- Acute exacerbation in fibrotic interstitial lung disease: an international working group report.American journal of respiratory and critical care medicine · 2026Review
- Meaningful thresholds for change in quantitative computed tomography-derived fibrosis extent in idiopathic pulmonary fibrosis.American journal of respiratory and critical care medicine · 2026Article
- Toward precision imaging in interstitial lung disease: advances in quantitative imaging and artificial intelligence.Current opinion in pulmonary medicine · 2026Review
- Non-Resolving Repair in Idiopathic Pulmonary Fibrosis: From Failed Cellular Transitions to Architectural Lock-In.International journal of molecular sciences · 2026Review
- Article
- Visibility of breathlessness in fibrotic interstitial lung disease: perceptions of international healthcare professionals.ERJ open research · 2026Article
- Application of the Idiopathic Pulmonary Fibrosis Patient-Reported Outcome Measure (IPF-PROM) scale to a Greek IPF patient population and its interrelation with depressive symptoms and health-related quality of life.BMJ open respiratory research · 2026Observational
- Aspects of Quality of Life in Interstitial Lung Disease: Pilot Observational Cross-Sectional Study in a Single Center.JMIR formative research · 2026Observational
- C/EBPγ interacts with C/EBPα and activates the β-catenin pathway in idiopathic pulmonary fibrosis.Cellular and molecular life sciences : CMLS · 2026Article
- Self-Reported Health-Related Quality of Life (HRQoL) in Adults With Urea Cycle Disorders.Journal of inherited metabolic disease · 2026Observational
- Article
Corrections and comments
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Authors and funding
38 authors.
Ganesh RaghuCenter for Interstitial Lung Diseases, Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine.ORCID 0000-0001-7506-6643
Marya GhazipuraZS Associates, Global Health Economics and Outcomes Research, New York, New York.ORCID 0000-0003-4328-6822
Thomas R FlemingDepartment of Biostatistics, University of Washington, Seattle, Washington.
Kerri I AronsonDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Weill Cornell Medicine, New York, New York.ORCID 0000-0001-5587-5427
Jürgen BehrDepartment of Medicine V, LMU University Hospital, Ludwig-Maximilians-University Munich, Member of the German Center for Lung Research, Munich, Germany.
Kevin K BrownDepartment of Medicine and.
Kevin R FlahertyDivision of Pulmonary and Critical Care, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
Ella A KazerooniDivision of Pulmonary and Critical Care, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
Toby M MaherDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.ORCID 0000-0001-7192-9149
Luca RicheldiDivisione di Medicina Polmonare, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID 0000-0001-8594-1448
Joseph A LaskyDepartment of Medicine, Tulane University, New Orleans, Louisiana.
Jeffrey J SwigrisDepartment of Medicine and.
Robert BuschDivision of Pulmonology, Allergy, and Critical Care, Office of Immunology and Inflammation, and.ORCID 0000-0003-0820-7164
Lili GarrardDivision of Biometrics III, Office of Biostatistics, Office of Translational Sciences, Center for Drug Evaluation and Research, and.
Dong-Hyun AhnDivision of Biometrics III, Office of Biostatistics, Office of Translational Sciences, Center for Drug Evaluation and Research, and.
Ji LiDivision of Clinical Outcome Assessment, Office of Drug Evaluation Sciences, Office of New Drugs, and.
Khalid PuthawalaDivision of Pulmonology, Allergy, and Critical Care, Office of Immunology and Inflammation, and.
Gabriela RodalOffice of Product Evaluation and Quality, Center for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, Maryland.
Sally SeymourDivision of Pulmonology, Allergy, and Critical Care, Office of Immunology and Inflammation, and.
Nargues WeirOffice of Product Evaluation and Quality, Center for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, Maryland.
Sonye K DanoffDivision of Pulmonary and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland.
Neil EttingerDivision of Pulmonary Medicine, St. Luke's Hospital, Chesterfield, Missouri.
Jonathan GoldinDepartment of Radiology, University of California, Los Angeles, Los Angeles, California.
Marilyn K GlassbergDepartment of Medicine, Stritch School of Medicine, Loyola Chicago, Chicago, Illinois.
Leticia Kawano-DouradoHcor Research Institute - Hcor Hospital, São Paolo, Brazil.ORCID 0000-0003-0784-1331
Nasreen KhalilDepartment of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Lisa LancasterDivision of Pulmonary, Critical Care, and Sleep Medicine, Vanderbilt University, Nashville, Tennessee.
David A LynchDepartment of Radiology, National Jewish Health, Denver, Colorado.ORCID 0000-0002-6329-2325
Yolanda MagetoDivision of Pulmonary, Critical Care, and Sleep Medicine, Baylor University, Dallas, Texas.
Imre NothDivision of Pulmonary and Critical Care Medicine, University of Virginia, Charlottesville, Virginia.ORCID 0000-0001-9846-5030
Jessica E ShorePulmonary Fibrosis Foundation, Chicago, Illinois.
Marlies WijsenbeekCentre of Interstitial Lung Diseases, Erasmus MC, University Medical Centre, Rotterdam, the Netherlands.
Robert BrownPatient representative and patient living with IPF, Lovettsville, Virginia.
Daniel GroganPatient representative and patient living with IPF, Charlottesville, Virginia; and.
Dorothy IveyPatient representative and patient living with IPF, Richmond, Virginia.
Patrycja GolinskaDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Weill Cornell Medicine, New York, New York.
Banu Karimi-ShahDivision of Pulmonology, Allergy, and Critical Care, Office of Immunology and Inflammation, and.
Fernando J MartinezDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Weill Cornell Medicine, New York, New York.ORCID 0000-0002-2412-3182
Funding
Rise-HP: Reimagining Interventions for Support and Education in Hypersensitivity Pneumonitis; A Stakeholder Engaged Intervention to Improve Health-Related Quality of LifeK23HL163394 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Kerri Aronson · 2022 to 2026
$942kNHLBI NIH HHS K23 HL163394
Abstract
PubMed holds no abstract for this paper.
Indexed as
Idiopathic Pulmonary FibrosisPatient AdvocacyClinical Trials as TopicHumansNational Institutes of Health (U.S.)Quality of LifeReproducibility of ResultsUnited StatesVital CapacityFVC, 6MWT, composite endpoint for IPF trialsidiopathic pulmonary fibrosisimage and circulatory biomarkers for IPF trialsmeaningful outcomes as endpoints for IPF trialspatient reported outcomes for IPF trials
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.