Evidence map›Paper›PMID 38174532›Full record

Trial reportIndian journal of pharmacology

The clinical effect of ossotide for injection in the treatment of condylar fracture.

Qian Jiang, Yifei Chen, Fangyong Zhu, Yujia Xie, Zhidan Zhu, Xiaojing Sun

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Indian journal of pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Qian JiangDepartment of Orthodontics, Affiliated Stomatological Hospital, Guilin Medical University, Guilin, China.
Yifei ChenSchool of Pharmacy, Guilin Medical University, Guilin, China.
Fangyong ZhuDepartment of Stomatology, Affiliated Hospital, Jiangnan University, Wuxi, China.
Yujia XieDepartment of Orthodontics, Affiliated Stomatological Hospital, Guilin Medical University, Guilin, China.
Zhidan ZhuDepartment of Orthodontics, Affiliated Stomatological Hospital, Guilin Medical University, Guilin, China.
Xiaojing SunDepartment of Orthodontics, Guilin Stomatological Hospital, Guilin, China.
Guilin Medical University · CNJiangnan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPatients with condylar fractures were treated with osteopeptide injections as an adjuvant therapy to assess pain control and changes in interleukin-1β (IL-1β) and bone G-gla protein (BGP) levels. MATERIALS AND

methodsEighty-two patients with a condylar neck fracture were randomly assigned to two groups. The control group received conventional surgical treatment, while the experimental group received osteopeptide injections in addition to surgery. Pain level, IL-1β, and BGP levels were evaluated at 1, 2, and 4 weeks postsurgery.

resultsOne and two weeks postsurgery, the experimental group had lower Numeric Rating Scale scores compared to the control group. In addition, the IL-1β level in patients receiving osteopeptide injections was lower than the control group at all three evaluation points (1, 2, and 4 weeks postsurgery) and the BGP level was higher with statistically significant differences (P < 0.05).

conclusionsThe administration of osteopeptide injections as an adjuvant therapy for patients with condylar fractures can effectively reduce pain and facilitate faster initiation of muscle function training. In addition, the reduction of inflammatory factors and promotion of active osteogenesis leads to quicker wound healing.

Indexed as

PainHumansInjectionsTreatment OutcomeBone G-gla proteincondylar fractureinterleukin-1βnumeric rating scale scoreossotide for injection

Identifiers

PMID38174532
PMCPMC10821697
OpenAlexW4390594969

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.