Evidence map›Paper›PMID 38174269›Full record

ArticleRSC advances2024

Novel pyrazoline linked acyl thiourea pharmacophores as antimicrobial, urease, amylase and α-glucosidase inhibitors: design, synthesis, SAR and molecular docking studies.

Aamer Saeed, Atteeque Ahmed, Main Bilal Haider, Hammad Ismail, Khizar Hayat, Ghulam Shabir, Hesham R El-Seedi

Abstract read
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Synthesis, structure and computational study ofActa crystallographica. Section E, Crystallographic communications · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Discovery ofFuture medicinal chemistry · 2025
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aamer SaeedDepartment of Chemistry, Quaid I Azam University Islamabad 45320 Pakistan asaeed@qau.edu.pk +92-51-9064-2241 +92-51-9064-2128.ORCID https://orcid.org/0000-0002-7112-9296
Atteeque AhmedDepartment of Chemistry, Quaid I Azam University Islamabad 45320 Pakistan asaeed@qau.edu.pk +92-51-9064-2241 +92-51-9064-2128.
Main Bilal HaiderDepartment of Chemistry, Quaid I Azam University Islamabad 45320 Pakistan asaeed@qau.edu.pk +92-51-9064-2241 +92-51-9064-2128.
Hammad IsmailDepartment of Biochemistry and Biotechnology, University of Gujrat Gujrat 50700 Pakistan.
Khizar HayatDepartment of Botany, University of Gujrat Gujrat 50700 Pakistan.
Ghulam ShabirDepartment of Chemistry, Quaid I Azam University Islamabad 45320 Pakistan asaeed@qau.edu.pk +92-51-9064-2241 +92-51-9064-2128.
Hesham R El-SeediInternational Research Centre for Food Nutrition and Safety, Jiangsu University Zhenjiang 212013 China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present work, a small library of novel pyrazolinyl-acyl thiourea (5a-j) was designed and synthesized through a multistep sequence and the synthesized compounds were screened for their antifungal, antibacterial and antioxidant activities as well as urease, amylase and α-glucosidase inhibitory activities. The synthesized series (5a-o) was characterized using a combination of spectroscopic techniques, including FT-IR,

Identifiers

PMID38174269
PMCPMC10759180

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.