ReviewArrhythmia & electrophysiology review2023
The Emerging Role of Left Bundle Branch Area Pacing for Cardiac Resynchronisation Therapy.
Review in Arrhythmia & electrophysiology review, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Left Bundle Branch Area Pacing Versus Biventricular Pacing in Cardiac Resynchronization Therapy: A Systematic Review and Meta-Analysis.Critical pathways in cardiology · 2026Pooled it
- Outcomes of Left Bundle Branch Area Pacing in Heart Failure Patients: A Systematic Review.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026Pooled it
- From Ophthalmoplegia to Multilevel Atrioventricular Block: Timing Cardiac Device Therapy in Kearns-Sayre Syndrome.JACC. Case reports · 2026Article
- Left bundle branch area pacing decreased the pressure gradient and severity of tricuspid regurgitation compared with right ventricular pacing.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Article
- Irreversible left-ventricular lead electrical failure from conductor externalization managed with left bundle branch area pacing: a case report.European heart journal. Case reports · 2026Article
- Resynchronisation efficacy of pacing strategies depends on the assessment metric: a computational study.Frontiers in physiology · 2026Article
- T Wave Oversensing in Left Bundle Branch Optimised CRT.Arrhythmia & electrophysiology review · 2026Article
- Left Bundle Branch Area Pacing Preserves Mechanical Strain and Synchrony Compared to Right Ventricular Apical Pacing in an Acute Paired Preclinical Model.bioRxiv : the preprint server for biology · 2025Article
- Apex vs. Septum Pacing: A Comprehensive Review of Pacemaker Implantation Strategies.Biomedicines · 2025Review
- Left bundle branch pacing cardiac resynchronization therapyWorld journal of cardiology · 2025Article
- Stylet-driven leads versus lumenless pacing leads in patients with left bundle branch area pacing: A systematic review and meta-analysis.Heart rhythm O2 · 2025Article
- Recent Advances in Cardiac Resynchronization Therapy: Current Treatment and Future Direction.Journal of clinical medicine · 2025Review
- Conduction System Pacing for CRT: A Physiological Alternative.Arrhythmia & electrophysiology review · 2025Review
- Complications, Troubleshooting and Follow-up for Left Bundle Branch Area Pacing.Arrhythmia & electrophysiology review · 2025Review
- Current Advance, Challenges and Future Perspectives of Conduction System Pacing.Reviews in cardiovascular medicine · 2024Review
- [New pacing strategies for heart failure].Innere Medizin (Heidelberg, Germany) · 2024Review
- Unlocking the Potential: Angiotensin Receptor Neprilysin and Sodium Glucose Co-Transporter 2 Inhibitors for Right Ventricle Dysfunction in Heart Failure.Medicina (Kaunas, Lithuania) · 2024Review
- Left Bundle Branch Area Pacing to Overcome Coronary Sinus Anatomy-Related Technical Problems Encountered during Implantation of Biventricular CRT-A Case Report.Journal of clinical medicine · 2024Article
- Left bundle branch pacing set to outshine biventricular pacing for cardiac resynchronization therapy?World journal of cardiology · 2024Article
- Conduction System Pacing in Children and Congenital Heart Disease.Arrhythmia & electrophysiology review · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiac resynchronisation therapy (CRT) reduces the risk of heart failure-related hospitalisations and all-cause mortality, as well as improving quality of life and functional status in patients with persistent heart failure symptoms despite optimal medical treatment and left bundle branch block. CRT has traditionally been delivered by implanting a lead through the coronary sinus to capture the left ventricular epicardium; however, this approach is associated with significant drawbacks, including a high rate of procedural failure, phrenic nerve stimulation, high pacing thresholds and lead dislodgement. Moreover, a significant proportion of patients fail to derive any significant benefit. Left bundle branch area pacing (LBBAP) has recently emerged as a suitable alternative to traditional CRT. By stimulating the cardiac conduction system physiologically, LBBAP can result in a more homogeneous left ventricular contraction and relaxation, thus having the potential to improve outcomes compared with conventional CRT strategies. In this article, the evidence supporting the use of LBBAP in patients with heart failure is reviewed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.