Evidence map›Paper›PMID 38173792›Full record

ArticleFrontiers in cellular and infection microbiology2023

Dynamical alterations of brain function and gut microbiome in weight loss.

Jing Zhou, Xiaoling Wu, Tianyuan Xiang, Fei Liu, Hui Gao, Li Tong, Bin Yan, Zhonglin Li, Chi Zhang, Linyuan Wang and 16 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Jing Zhou *Henan Provincial Research Center of Clinical Medicine of Nephropathy, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan University People's Hospital, Zhengzhou, China.
Xiaoling Wu *Department of Nuclear Medicine, Henan Key Laboratory of Chronic Disease Health Management, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, Henan, China.
Tianyuan Xiang *Health Management Institute, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Fei Liu *Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Hui GaoHenan Key Laboratory of Imaging and Intelligent Processing, People's Liberation Army (PLA) Strategic Support Force Information Engineering University, Zhengzhou, Henan, China.
Li TongHenan Key Laboratory of Imaging and Intelligent Processing, People's Liberation Army (PLA) Strategic Support Force Information Engineering University, Zhengzhou, Henan, China.
Bin YanHenan Key Laboratory of Imaging and Intelligent Processing, People's Liberation Army (PLA) Strategic Support Force Information Engineering University, Zhengzhou, Henan, China.
Zhonglin LiDepartment of Radiology, Henan Provincial People's Hospital, Zhengzhou, Henan, China.
Chi ZhangHenan Key Laboratory of Imaging and Intelligent Processing, People's Liberation Army (PLA) Strategic Support Force Information Engineering University, Zhengzhou, Henan, China.
Linyuan WangHenan Key Laboratory of Imaging and Intelligent Processing, People's Liberation Army (PLA) Strategic Support Force Information Engineering University, Zhengzhou, Henan, China.
Lei OuHealth Management Institute, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Zhongxia LiBYHEALTH Institute of Nutrition & Health, BYHEALTH Co. Ltd, Guangzhou, Guangdong, China.
Wen WangDepartment of Nutrition, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan, Zhengzhou, China.
Tingting YangDepartment of Nutrition, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan, Zhengzhou, China.
Fengyun LiDepartment of Health Management, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan University People's Hospital, Zhengzhou, Henan, China.
Huimin MaDepartment of Health Management, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan University People's Hospital, Zhengzhou, Henan, China.
Xiaojuan ZhaoDepartment of Health Management, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan University People's Hospital, Zhengzhou, Henan, China.
Na MiDepartment of Health Management, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan University People's Hospital, Zhengzhou, Henan, China.
Ziya YuHenan Key Laboratory of Imaging and Intelligent Processing, People's Liberation Army (PLA) Strategic Support Force Information Engineering University, Zhengzhou, Henan, China.
Canhui LanBeijing Rexinchang Biotechnology Research Institute Co. Ltd, Beijing, China.
Qi WangCuiying Biomedical Research Center, Lanzhou University Second Hospital, Lanzhou, Gansu, China.
Hao LiDepartment of Health Management, Fuwai Central China Cardiovascular Hospital, Zhengzhou, China.
Liming WangInstitute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Xiaoning WangThe Institute of Geriatrics, The State Clinic Center for Geriatrics & The State Key Laboratory of Kidney, The People's Liberation Army (PLA) General Hospital, Beijing, China.
Yongli LiDepartment of Health Management, Henan Key Laboratory of Chronic Disease Management, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan University People's Hospital, Zhengzhou, Henan, China.
Qiang ZengHealth Management Institute, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Intermittent energy restriction (IER) is an effective weight loss strategy. However, little is known about the dynamic effects of IER on the brain-gut-microbiome axis. Methods: In this study, a total of 25 obese individuals successfully lost weight after a 2-month IER intervention. FMRI was used to determine the activity of brain regions. Metagenomic sequencing was performed to identify differentially abundant gut microbes and pathways in from fecal samples. Results: Our results showed that IER longitudinally reduced the activity of obese-related brain regions at different timepoints, including the inferior frontal orbital gyrus in the cognitive control circuit, the putamen in the emotion and learning circuit, and the anterior cingulate cortex in the sensory circuit. IER longitudinally reduced Conclusions: There was dynamical alteration of BGM axis (the communication of

Indexed as

Gastrointestinal MicrobiomeCaloric RestrictionEscherichia coliHumansObesityWeight Lossbrain-gut-microbiome axisfunctional magnetic resonance imagingintermittent energy restrictionmetagenomicsweight loss

Identifiers

PMID38173792
PMCPMC10761423

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.