Evidence map›Paper›PMID 38173778›Full record

ArticleRegenerative biomaterials2024

Byakangelicol suppresses TiPs-stimulated osteoclastogenesis and bone destruction via COX-2/NF-κB signaling pathway.

Zhidong Wang, Huaqiang Tao, Miao Chu, Lei Yu, Peng Yang, Qiufei Wang, Jun Lu, Huilin Yang, Zhenheng Wang, Hailin Zhang and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Regenerative biomaterials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Zhidong WangDepartment of Orthopedics, The First Affiliated Hospital of Soochow University, No. 188 Shizi Street, Suzhou 215000, China.
Huaqiang TaoDepartment of Orthopedics, The First Affiliated Hospital of Soochow University, No. 188 Shizi Street, Suzhou 215000, China.
Miao ChuDepartment of Orthopedics, The First Affiliated Hospital of Soochow University, No. 188 Shizi Street, Suzhou 215000, China.
Lei YuDepartment of Orthopedics, The First Affiliated Hospital of Soochow University, No. 188 Shizi Street, Suzhou 215000, China.
Peng YangDepartment of Orthopedics, The First Affiliated Hospital of Soochow University, No. 188 Shizi Street, Suzhou 215000, China.
Qiufei WangDepartment of Orthopedics, Changshu Hospital Affiliated to Soochow University, First People's Hospital of Changshu City, Changshu 215500, China.
Jun LuDivision of Sports Medicine and Adult Reconstructive Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, 321 Zhong Shan Road, Nanjing 210000, China.
Huilin YangDepartment of Orthopedics, The First Affiliated Hospital of Soochow University, No. 188 Shizi Street, Suzhou 215000, China.
Zhenheng WangDepartment of Orthopedics, The First Affiliated Hospital of Soochow University, No. 188 Shizi Street, Suzhou 215000, China.
Hailin ZhangDepartment of Orthopedics, Jiangyin People's Hospital Affiliated to Nantong University, No. 163 Shoushan Road, Jiangyin 214400, China.
Dechun GengDepartment of Orthopedics, The First Affiliated Hospital of Soochow University, No. 188 Shizi Street, Suzhou 215000, China.ORCID https://orcid.org/0000-0003-4375-2803
Soochow University · CNJiangyin People's Hospital · CNNanjing Drum Tower Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aseptic loosening (AL) is considered a significant cause of prosthesis revision after arthroplasty and a crucial factor in the longevity of an artificial joint prosthesis. The development of AL is primarily attributed to a series of biological reactions, such as peri-prosthetic osteolysis (PPO) induced by wear particles around the prosthesis. Chronic inflammation of the peri-prosthetic border tissue and hyperactivation of osteoclasts are key factors in this process, which are induced by metallic wear particles like Ti particles (TiPs). In our

Indexed as

byakangelicolCOX-2inflammationNF-κBTiPs

Identifiers

PMID38173778
PMCPMC10758544
OpenAlexW4387934139

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.