ArticleRSC advances2024
Green synthesized gold nanoparticles and CuO-based nonenzymatic sensor for saliva glucose monitoring.
Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 37 citations in OpenAlex.
- Synthesis and characterization of Ag doped CuO nanorods electrode for non-enzymatic glucose sensing.Scientific reports · 2026Article
- Current status and future challenges of transition-metal oxides as enzyme-mimetics for detection of clinically relevant biomarkers: a comprehensive review.Mikrochimica acta · 2026Review
- Hydroxyethyl cellulose-based ZnCeRSC advances · 2026Article
- Interface engineering of carbon-doped Cu/CuMikrochimica acta · 2025Article
- A fluorescent biosensor based on glucose oxidase-DNAzyme/substrate complex synergy for salivary glucose monitoring.Analytical and bioanalytical chemistry · 2025Article
- Gold nanoparticle-modified screen-printed carbon electrodes for label-free detection of SARS-CoV-2 RNA using drop casting and spray coating methods.ADMET & DMPK · 2025Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
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Abstract
Glucose, essential for brain and muscle functions, requires careful monitoring in diabetes and other chronic disease management. While blood glucose monitoring provides precise information about these diseases, it remains an invasive method. Saliva glucose monitoring could offer an alternative approach, but the glucose concentration in saliva is very low. In this work, we report a simple, low-cost, highly sensitive nonenzymatic electrochemical glucose sensor. We developed this sensor using green synthesized gold nanoparticles (AuNPs) and wet chemical synthesized copper oxide (CuO) nanoparticles on a screen-printed carbon electrode (Au/CuO/SPCE). The sensor's high sensitivity results from dual amplification strategies using AuNPs and CuO nanomaterials, each demonstrating catalytic activity towards glucose. This shows promising potential for saliva glucose monitoring. The AuNPs were synthesized using an Au precursor and orange peel extract (OPE), yielding stable colloidal AuNPs with a mean diameter of about 37 nm, thus eliminating the need for additional capping agents. Under optimal conditions, amperometric tests revealed that the sensor responded linearly to glucose concentrations ranging from 2 μM to 397 μM with a sensitivity of 236.70 μA mM
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Registered trials
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