Evidence map›Paper›PMID 38173229›Full record

ArticleIntestinal research2024

Assessing quality of magnetic resonance enterography and its impact on disease assessment of ileal Crohn's disease.

Anuj Bohra, Declan J Connoley, Danny Con, Jonathan P Segal, Olga Niewiadomski, Abhinav Vasudevan, Daniel R Van Langenberg, Numan Kutaiba

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Article in Intestinal research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Motion Mitigation Techniques for Abdominal and Cardiac MR Imaging.Journal of magnetic resonance imaging : JMRI · 2026
    Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Anuj BohraDepartment of Gastroenterology, Box Hill Hospital, Box Hill, Australia.
Declan J ConnoleyDepartment of Gastroenterology, Box Hill Hospital, Box Hill, Australia.
Danny ConDepartment of Gastroenterology, Box Hill Hospital, Box Hill, Australia.
Jonathan P SegalDepartment of Gastroenterology, The Royal Melbourne Hospital, Parkville, Australia.
Olga NiewiadomskiDepartment of Gastroenterology, Box Hill Hospital, Box Hill, Australia.
Abhinav VasudevanDepartment of Gastroenterology, Box Hill Hospital, Box Hill, Australia.
Daniel R Van LangenbergDepartment of Gastroenterology, Box Hill Hospital, Box Hill, Australia.
Numan KutaibaDepartment of Radiology, Box Hill Hospital, Box Hill, Australia.

Funding

Australian Government Research Training Program
6 · The paper itself

Abstract

BACKGROUND/

aimsAssessment of quality of magnetic resonance enterography (MRE) in small bowel Crohn's disease (CD) activity evaluation has received little attention. We assessed the impact of bowel distention and motion artifact on MRE activity indices in ileal CD.

methodsA cohort of patients who underwent contemporaneous MRE and colonoscopy for ileal CD assessment between 2014 and 2021 at 2 centers were audited. An abdominal radiologist blinded to clinical data reviewed each MRE, graded bowel distention and motion artifact upon a pre-specified 3-point scale and calculated the original magnetic resonance index of activity (MaRIA) and simplified MaRIA (sMaRIA), London index and CD MRE index (CDMI). Ileal endoscopic activity was graded via the Simplified Endoscopy Score for CD (SES-CD). The performance of MRE indices in discriminating active disease (SES-CD ≥3) stratified by MRE quality was measured by receiver operator characteristic analyses.

resultsOne hundred and thirty-seven patients had MRE and colonoscopy within a median of 16 days (range, 0-30 days) with 63 (46%) exhibiting active disease (SES-CD ≥3). Forty-four MREs (32%) were deemed low quality due to motion artifact and/or moderate to poor distention. Low-quality MREs demonstrated reduced discriminative performance between ileal SES-CD ≥3 and MRE indices (MaRIA 0.838 vs. 0.634, sMaRIA 0.834 vs. 0.527, CDMI 0.850 vs. 0.595, London 0.748 vs. 0.511, P<0.05 for all). Individually the presence of any motion artifact markedly impacted the discriminative performance (e.g., sMaRIA area under the curve 0.544 vs. 0.814, P<0.05).

conclusionsImage quality parameters can significantly impact MRE disease activity interpretation. Quality metrics should be reported, enabling cautious interpretation in lower-quality studies.

Indexed as

Crohn diseaseDiagnostic imagingIntestine, small

Identifiers

PMID38173229
PMCPMC11079513

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.