Evidence map›Paper›PMID 38172825›Full record

ArticleBMC urology2024

Type 2 diabetes mellitus increases the risk of circumcision among men aged between 30 and 69 years using a nationwide population-based dataset in Taiwan: a five-year follow-up study.

Yun-Rui Wu, Yi-Horng Lai, Chung-Cheng Wang

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Article in BMC urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Yun-Rui WuDepartment of Urology, College of Medicine, En Chu Kong Hospital, National Taiwan University, 399 Fu-hsing Road, Sanxia District, New Taipei City, 23702, Taiwan.
Yi-Horng LaiDepartment of Healthcare Administration, Asia Eastern University of Science and Technology, New Taipei City, 22061, Taiwan.
Chung-Cheng WangDepartment of Urology, College of Medicine, En Chu Kong Hospital, National Taiwan University, 399 Fu-hsing Road, Sanxia District, New Taipei City, 23702, Taiwan. ericwcc@ms27.hinet.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetes is an important factor in the development of penile inflammation. We studied whether type 2 diabetes (DM), with/without hypertension and hyperlipidemia increased the risk of circumcision among men aged between 30 and 69 using a population-based dataset in Taiwan during a 5-year follow-up period.

methodsThe research data in this study were obtained from Taiwan's National Health Insurance Research Database between 1997 and 2010. We identified 23,197 patients who had a new diagnosis of DM and randomly matched 115,985 subjects as controls. We observed whether circumcision was the treatment after a new DM diagnosis. The initial step involved analyzing the data using Poisson regression analysis. To address potential confounding factors, this study employed propensity score matching based on three variables. Additionally, a Cox regression with a Gamma frailty was utilized to compare outcomes between different groups.

resultsPoisson regression analysis showed that DM (RR = 1.75, 95CI = 0.10 ~ 1.22), but not hypertension (RR = 1.14, 95CI=-0.44 ~ 0.70), hyperlipidemia (RR = 0.94, 95CI=-0.66 ~ 0.53), or age (RR = 0.83, 95CI=-0.43 ~ 0.62), had an impact on circumcision treatment. Cox regression with a frailty model found that DM was a risk factor associated with circumcision (HR = 2.31, 95% CI = 1.74 ~ 3.06, p-value < 0.01), whereas no significant difference was noted between circumcision and hypertension (HR = 1.10, 95% CI = 0.80 ~ 1.51), hyperlipidemia (HR = 1.05, 95% CI = 0.79 ~ 1.40), or age (HR = 1.00, 95% CI = 0.99 ~ 1.02).

conclusionsType 2 diabetes mellitus, but not hypertension, hyperlipidemia or age increases the risk of circumcision in men aged between 30 and 69 years.

Indexed as

Diabetes MellitusDiabetes Mellitus, Type 2FrailtyHyperlipidemiasHypertensionAdultAgedFollow-Up StudiesHumansIncidenceMaleMiddle AgedRetrospective StudiesRisk FactorsTaiwanCircumcisionDiabetes MellitusEpidemiology

Identifiers

PMID38172825
PMCPMC10765904

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.