Evidence map›Paper›PMID 38172764›Full record

ArticleBMC medical imaging2024

Assessment of water enema PET/CT: an effective imaging technique for the diagnosis of incidental colorectal

Rongqin Zhang, Meilinuer Abudurexiti, Wanglin Qiu, Pinbo Huang, Ping Hu, Wei Fan, Zhanwen Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC medical imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Rongqin Zhang *Department of Nuclear Medicine, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, China.
Meilinuer Abudurexiti *Department of Nuclear Medicine, The First People's Hospital of Xinjiang Kashgar Area, Kashgar, Xinjiang, 844000, China.
Wanglin QiuDepartment of Nuclear Medicine and Molecular Imaging, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China.
Pinbo HuangDepartment of Hepatobiliary Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.
Ping HuDepartment of Nuclear Medicine and Molecular Imaging, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China.
Wei FanDepartment of Nuclear Medicine, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, China. fanwei@sysucc.org.cn.
Zhanwen ZhangDepartment of Nuclear Medicine and Molecular Imaging, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China. zhzhanw7@mail.sysu.edu.cn.
Sun Yat-sen University · CNKashi University · CNSun Yat-sen Memorial Hospital · CNSun Yat-sen University Cancer Center · CN

Funding

National Natural Science Foundation of China No.81901772National Natural Science Foundation of China No.82172611Natural Science Foundation of Guangdong Province No.2019A1515011893Natural Science Foundation of Guangdong Province No.2022A1515012205the State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia & The First People's Hospital of Kashi Fund No.SKL-HIDCA-2020-KS2
6 · The paper itself

Abstract

backgroundTo validate the feasibility of water enema PET/CT (WE-PET/CT) in incidental colorectal

methodsWe retrospectively analysed the electronic records of 338 patients undergoing common PET/CT and WE-PET/CT at our hospital. PET/CT results were correlated with colonoscopy pathology and follow-up results. The ROC contrast curve was plotted to evaluate the accuracy of SUVmax on common PET/CT and WE-PET/CT for detecting neoplastic lesions. SUVmax and the median retention indexes (RIs) of cancerous, precancerous, and benign lesions and physiologic uptake were compared.

resultsThe sensitivity, specificity and accuracy of diagnosing neoplastic lesions with common PET/CT were 84.0%, 78.3% and 80.2%, respectively. The corresponding results with WE-PET/CT were 95.8%, 96.5% and 96.2%. The AUC of SUVmax on WE-PET/CT was significantly higher than that on common PET/CT (0.935 vs. 0.524, p < 0.001). The median SUVmax on WE-PET/CT was significantly higher than that on common PET/CT in cancerous and precancerous lesions, and significantly decreased in benign lesions and physiologic uptake (p < 0.001). The RI was significantly different between cancerous lesions and physiologic uptake, between precancerous lesions and physiologic uptake, between benign lesions and physiologic uptake, and between cancerous and benign lesions (p < 0.05).

conclusionsWE-PET/CT is a noninvasive, well-tolerated and effective technique for diagnosing incidental colorectal

Indexed as

Colorectal NeoplasmsPrecancerous ConditionsEnemaFluorodeoxyglucose F18HumansIncidental FindingsPositron-Emission TomographyPositron Emission Tomography Computed TomographyRadiopharmaceuticalsRetrospective StudiesWaterFluorodeoxyglucose F18RadiopharmaceuticalsWaterColorectal 18F-FDG uptakeIncidental colorectal lesionsPositron emission tomographyWater enema

Identifiers

PMID38172764
PMCPMC10765618
OpenAlexW4390571922

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.