Evidence map›Paper›PMID 38172702›Full record

ArticleBMC infectious diseases2024

Viability predictive factors of the daughter vesicles in hepatic cystic echinococcosis.

Aymen Trigui, Nahed Khmekhem, Sami Fendri, Rahma Daoud, Amira Akrout, Jihene Trabelsi, Rafik Mzali, Fatma Cheikhrouhou, Ali Ayadi, Chadli Dziri and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Aymen TriguiFaculty of Medicine, Department of General and Digestive Surgery, University of Sfax, Habib Bourguiba Hospital, Sfax, 3029, Tunisia. ayman.trigui@gmail.com.
Nahed KhmekhemFaculty of Medicine, Department of Parasitology and Mycology, University of Sfax, Habib Bourguiba Hospital, Sfax, Tunisia.
Sami FendriFaculty of Medicine, Department of General and Digestive Surgery, University of Sfax, Habib Bourguiba Hospital, Sfax, 3029, Tunisia.
Rahma DaoudFaculty of Medicine, Department of General and Digestive Surgery, University of Sfax, Habib Bourguiba Hospital, Sfax, 3029, Tunisia.
Amira AkroutFaculty of Medicine, Department of General and Digestive Surgery, University of Sfax, Habib Bourguiba Hospital, Sfax, 3029, Tunisia.
Jihene TrabelsiFaculty of Medicine, Department of Epidemiology, University of Sfax, Hedi Cheker Hospital, Sfax, Tunisia.
Rafik MzaliFaculty of Medicine, Department of General and Digestive Surgery, University of Sfax, Habib Bourguiba Hospital, Sfax, 3029, Tunisia.
Fatma CheikhrouhouFaculty of Medicine, Department of Parasitology and Mycology, University of Sfax, Habib Bourguiba Hospital, Sfax, Tunisia.
Ali AyadiFaculty of Medicine, Department of Parasitology and Mycology, University of Sfax, Habib Bourguiba Hospital, Sfax, Tunisia.
Chadli DziriGeneral Surgery, Honoris Medical Simulation Center Director, Medical school of Tunis, University El Manar, Tunis, Tunisia.
Mohamed Ben AmarFaculty of Medicine, Department of General and Digestive Surgery, University of Sfax, Habib Bourguiba Hospital, Sfax, 3029, Tunisia.
Saleh BoujelbeneFaculty of Medicine, Department of General and Digestive Surgery, University of Sfax, Habib Bourguiba Hospital, Sfax, 3029, Tunisia.
Hopital Universitaire Habib Bourguiba · TNUniversity of Sfax · TNTunis El Manar University · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionManagement of cystic echinococcosis (CE) requires knowledge of certain aspects related to the survival of Echinococcus granulosus. The viability of daughter vesicles (DV) is a determining factor in guiding therapeutic indications, particularly for transiently active Cysts type CE3b. PURPOSE: To determine the predictive factors of DV viability and its impact on the therapeutic management of CE3b type. MATERIALS AND

methodsThis is a prospective pilot study with an analytical aim on patients with cystic echinococcosis of the liver type CE2 and CE3b, operated in the General Surgery Department of Habib-Bourguiba Academic Hospital, Sfax-Tunisia for 22 months from March 2018 until December 2019. The unit of the study is the DV. A parasitological study of the DV was done in the parasitology laboratory.

resultsDuring the study period, 27 (40.9%) of 66 operated CE Disease from 21 patients containing 248 DV were explored. The median viability of DV protoscoleces was 16.7%. In bivariate analysis, factors for viability of DV protoscoleces were: fever, acute cholangitis, hyperbilirubinemia, left liver location, rock water and bilious echinococcal fluid (EF), cyst size ≥ 43 mm, Intracystic pressure ≥ 35 mmHg, DV size ≥ 6.5 mm, volume, number of DV/cyst ≥ 5, and opaque wall (p < 0.05). Predictive factors for the Non-viability of DV were: CE3b type, purulent EF, gelatinous EF. In multivariate analysis, only CE2 type, cyst size ≥ 43 mm, number of DV/cyst ≥ 5 and DV size ≥ 6.5 mm were factors significantly associated with the viability of DV protoscoleces.

conclusionCE3b cysts without the criteria of viability of DV protoscoleces may become candidates for the 'Wait-and-Watch' procedure.

Indexed as

CystsEchinococcosisEchinococcosis, HepaticEchinococcusEchinococcus granulosusAnimalsHumansNuclear FamilyPilot ProjectsProspective StudiesDaughter vesiclesEchinococcus InfectionHepatic

Identifiers

PMID38172702
PMCPMC10765707
OpenAlexW4390534574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.