ArticleNature2024
Na
Open access · hybridAbstract read
In one paragraph
Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.
0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
45.6field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
74 citing papers in PubMed, 97 citations in OpenAlex.
- 15-PGDH inhibition in osteoarthritis: PGEBone research · 2026Review
- Emerging therapies for knee osteoarthritis.Nature reviews. Rheumatology · 2026Review
- Soluble Nanomedicine Against Soluble Neurosensitizers to Effectively Relieve Osteoarthritis Pain and Joint Damage.Exploration (Beijing, China) · 2026Article
- Antigen-Detected NMR for Minimal Epitope Engineering and Structure-Guided Selection of a NaAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Ion-Channel Activity of Characteristic Alkaloids From Uncaria rhynchophylla.Chemistry & biodiversity · 2026Article
- Targeting FOSL1-KCa3.1 inhibits ferroptosis and cartilage destruction by suppressing mitochondrial hyperfusion.Acta pharmacologica Sinica · 2026Article
- Collagen II hydrogel-mediated sustained delivery of lacosamide attenuates cartilage degeneration and pain in osteoarthritis.Bioactive materials · 2026Article
- Piezo2 Mediates a Vicious Cycle of "Mechanical Homeostasis Imbalance-Inflammation" in Sensory Nerves and the Cartilage Endplate.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Synergistic targeting of senolytic and senomorphic action with dual-engineered biomimetic macrophage nanovesicles for mitigating osteoarthritis.Bioactive materials · 2026Article
- Targeting MDK alleviates bone loss via dual regulation of osteogenic differentiation and inflammatory cytokine expression.Genes & diseases · 2026Article
- A Photothermal Transducer Regulates Transmembrane Calcium Flow for Synergistic Osteoarthritis Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Cartilage targeting hydrogel nanoplatform degrades BRD4 to alleviate osteoarthritis via Nav1.7 axis.Nature communications · 2026Article
- Mapping the Extended Pain Pathway: Human Genetic and Multi-Omic Strategies for Next-Generation Analgesics.International journal of molecular sciences · 2026Review
- Dapagliflozin regulates chondrocyte homeostasis and protects against osteoarthritis via targets AMPKα and SGLT2.Cell death discovery · 2026Article
- Osteoarthritis: molecular pathogenesis and potential therapeutic options.Signal transduction and targeted therapy · 2026Review
- Targeted Inhibition of CD74Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Interorgan Communications in Skeletal Pathophysiology: From Molecular Pathways to Multidisciplinary Therapies.Research (Washington, D.C.) · 2026Review
- Revisiting the Subtle Relationship Between Metabolic Syndrome and Osteoarthritis.Journal of inflammation research · 2026Review
- Sono-piezoelectric cues regulate neuroinflammatory reflex-arc-mediated α7nAChR-P2RX7 axis to dampen osteoarthritis-correlated pain with osteoarthritis attenuation.Theranostics · 2026Article
- Neuroimmune crosstalk in osteoarthritis pain: from synovial inflammation to pain sensitization.Frontiers in immunology · 2026Review
14 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
27 authors at 4 institutions in 1 country.
Wenyu FuDepartment of Orthopaedic Surgery, New York University Grossman School of Medicine, New York, NY, USA.ORCID 0000-0002-4520-1506
Dmytro VasylyevDepartment of Neurology, Yale School of Medicine, New Haven, CT, USA.
Yufei BiDepartment of Orthopaedic Surgery, New York University Grossman School of Medicine, New York, NY, USA.
Mingshuang ZhangDepartment of Orthopaedic Surgery, New York University Grossman School of Medicine, New York, NY, USA.
Guodong SunDepartment of Orthopaedic Surgery, New York University Grossman School of Medicine, New York, NY, USA.
Asya KhleborodovaDepartment of Orthopaedic Surgery, New York University Grossman School of Medicine, New York, NY, USA.
Guiwu HuangDepartment of Orthopaedic Surgery, New York University Grossman School of Medicine, New York, NY, USA.
Libo ZhaoDepartment of Orthopaedic Surgery, New York University Grossman School of Medicine, New York, NY, USA.
Renpeng ZhouDepartment of Orthopaedic Surgery, New York University Grossman School of Medicine, New York, NY, USA.
Yonggang LiDepartment of Orthopaedic Surgery, New York University Grossman School of Medicine, New York, NY, USA.
Shujun LiuDepartment of Neurology, Yale School of Medicine, New Haven, CT, USA.
Xianyi CaiDepartment of Orthopaedic Surgery, New York University Grossman School of Medicine, New York, NY, USA.
Wenjun HeDepartment of Orthopaedic Surgery, New York University Grossman School of Medicine, New York, NY, USA.
Min CuiDepartment of Orthopaedic Surgery, New York University Grossman School of Medicine, New York, NY, USA.
Xiangli ZhaoDepartment of Orthopaedic Surgery, New York University Grossman School of Medicine, New York, NY, USA.
Aubryanna HettinghouseDepartment of Orthopaedic Surgery, New York University Grossman School of Medicine, New York, NY, USA.
Julia GoodDepartment of Orthopaedic Surgery, New York University Grossman School of Medicine, New York, NY, USA.
Ellen KimDepartment of Orthopaedic Surgery, New York University Grossman School of Medicine, New York, NY, USA.
Eric StraussDepartment of Orthopaedic Surgery, New York University Grossman School of Medicine, New York, NY, USA.
Philipp LeuchtDepartment of Orthopaedic Surgery, New York University Grossman School of Medicine, New York, NY, USA.
Ran SchwarzkopfDepartment of Orthopaedic Surgery, New York University Grossman School of Medicine, New York, NY, USA.
Edward X GuoDepartment of Biomedical Engineering, Columbia University, New York, NY, USA.
Jonathan SamuelsDivision of Rheumatology, Department of Medicine, New York University Grossman School of Medicine, New York, NY, USA.
Wenhuo HuHuman Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0002-8686-7160
Mukundan AtturDivision of Rheumatology, Department of Medicine, New York University Grossman School of Medicine, New York, NY, USA.ORCID 0000-0001-7080-8118
Stephen G WaxmanDepartment of Neurology, Yale School of Medicine, New Haven, CT, USA. stephen.waxman@yale.edu.ORCID 0000-0001-5718-7177
Chuan-Ju LiuDepartment of Orthopaedic Surgery, New York University Grossman School of Medicine, New York, NY, USA. chuan-ju.liu@yale.edu.ORCID 0000-0002-7181-8032
New York University · USYale University · USColumbia University · USMemorial Sloan Kettering Cancer Center · US
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4MThe immunological mechanism of PGRNs anti-inflammatory effect - Renewal - 1R01AR062207 · NIAMS · YALE UNIVERSITY · PI Chuanju Liu · 2012 to 2026
$5.6MThe Role of PGRN Growth Factor in Osteoarthritis. - Renewal - 1 - Revision - 2R01AR061484 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LIU, CHUANJU · 2011 to 2020
$4.8MProgranulin: A Novel Gene in Gaucher DiseasesR01NS103931 · NINDS · YALE UNIVERSITY · PI Chuanju Liu, Ying Sun · 2017 to 2026
$4.3MThe Role of Sodium Channel Nav1.7 in Osteoarthritis - Resubmission - 1R01AR078035 · NIAMS · YALE UNIVERSITY · PI Chuanju Liu, Stephen Waxman · 2022 to 2026
$2.8MTargeting TNF Receptors to Inhibit Inflammation and to Prompt Bone Regeneration in Type 1 Diabetes - Resubmission - 1R01AR076900 · NIAMS · YALE UNIVERSITY · PI LIU, CHUANJU · 2020 to 2024
$2.0MNCI NIH HHS P30 CA008748NIAMS NIH HHS R01 AR061484NIAMS NIH HHS R01 AR062207NIAMS NIH HHS R01 AR076900NIAMS NIH HHS R01 AR078035NINDS NIH HHS R01 NS103931
Abstract
Osteoarthritis (OA) is the most common joint disease. Currently there are no effective methods that simultaneously prevent joint degeneration and reduce pain
Indexed as
ChondrocytesNAV1.7 Voltage-Gated Sodium ChannelOsteoarthritisVoltage-Gated Sodium Channel BlockersAnimalsCalciumCalcium SignalingDisease ProgressionGanglia, SpinalHumansMiceMicrotubule-Associated ProteinsNeuronsPainCalciumMicrotubule-Associated ProteinsNAV1.7 Voltage-Gated Sodium ChannelNAV1 protein, humanNav1 protein, mouseVoltage-Gated Sodium Channel Blockers
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.