Evidence map›Paper›PMID 38172630›Full record

ArticleNature human behaviour2024

Driving and suppressing the human language network using large language models.

Greta Tuckute, Aalok Sathe, Shashank Srikant, Maya Taliaferro, Mingye Wang, Martin Schrimpf, Kendrick Kay, Evelina Fedorenko

Abstract read
PubMed Publisher
In one paragraph

Article in Nature human behaviour, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Making models disagree to learn how brains compute.Nature reviews. Neuroscience · 2026
    Review
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  6. Article
  7. Deep Sound Synthesis Matched to Brain Activity Recapitulates Preferential Responses to Speech and Music.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  8. Article
  9. Review
  10. Sensory encoding of emotion conveyed by the face and visual context.Social cognitive and affective neuroscience · 2026
    Article
  11. Do Language Models Know Who Did What to Whom?Open mind : discoveries in cognitive science · 2026
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. The cerebellar components of the human language network.bioRxiv : the preprint server for biology · 2025
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Greta TuckuteDepartment of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA. gretatu@mit.edu.ORCID 0000-0002-5572-5469
Aalok SatheDepartment of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID 0000-0002-5248-7557
Shashank SrikantComputer Science & Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA.
Maya TaliaferroDepartment of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
Mingye WangDepartment of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
Martin SchrimpfMcGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID 0000-0001-7766-7223
Kendrick KayCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, USA.
Evelina FedorenkoDepartment of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA. evelina9@mit.edu.ORCID 0000-0003-3823-514X

Funding

U.S. Department of Health & Human Services | NIH | NIH Blueprint for Neuroscience Research R01-DC016607U.S. Department of Health & Human Services | NIH | NIH Blueprint for Neuroscience Research R01-DC016950U.S. Department of Health & Human Services | NIH | NIH Blueprint for Neuroscience Research U01- NS121471
6 · The paper itself

Abstract

Transformer models such as GPT generate human-like language and are predictive of human brain responses to language. Here, using functional-MRI-measured brain responses to 1,000 diverse sentences, we first show that a GPT-based encoding model can predict the magnitude of the brain response associated with each sentence. We then use the model to identify new sentences that are predicted to drive or suppress responses in the human language network. We show that these model-selected novel sentences indeed strongly drive and suppress the activity of human language areas in new individuals. A systematic analysis of the model-selected sentences reveals that surprisal and well-formedness of linguistic input are key determinants of response strength in the language network. These results establish the ability of neural network models to not only mimic human language but also non-invasively control neural activity in higher-level cortical areas, such as the language network.

Indexed as

ComprehensionLanguageBrainBrain MappingHumansLinguistics

Identifiers

PMID38172630

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.