ArticleNature microbiology2024
Leaf microbiome dysbiosis triggered by T2SS-dependent enzyme secretion from opportunistic Xanthomonas pathogens.
Article in Nature microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
35 citing papers in PubMed, 51 citations in OpenAlex.
- Engineering rhizobacterial communities for soil and plant health.Microbiology (Reading, England) · 2026Review
- The plant holobiont: integrating molecular priming and ecological legacies for climate-adaptive immunity.Essays in biochemistry · 2026Review
- Comparative genomics of strains of varying virulence of the gram-positive bacterial pathogen of maize, Clavibacter nebraskensis.BMC genomics · 2026Article
- Emerging Threats in Southern U.S. Pine Plantations: Temporal Dynamics of Fungal Communities and the Impact of Lecanosticta acicola.Microbial ecology · 2026Article
- Genome Evolution in Plant Pathogenic Bacteria.Genome biology and evolution · 2026Review
- Genomic and enzymatic signatures underlying lifestyle diversity inMicrobial genomics · 2026Article
- Distinct filtering processes shape bacterial and fungal communities and their co-occurrence patterns across garlic-associated compartments.Environmental microbiome · 2026Article
- Metabolic feedbacks drive population dynamics and can lead to oscillations among leaf bacteria.Nature communications · 2026Article
- Unlocking the genetic arsenal of Xanthomonas arboricola: new insights into taxonomic classification, pathogenicity and adaptation beyond the effectorome.BMC genomics · 2026Article
- Microbial community succession and dynamics during the season-long development of apple fruit (Microbiology spectrum · 2026Article
- Plant health in the era of global changes, holobiont biology, and microbiome-based solutions.Horticulture research · 2026Article
- Phenolic acid biosynthesis is associated with deleterious microbiome changes during Plasmodiophora brassicae-induced clubroot in pakchoi.Microbiome · 2026Article
- Reactive oxygen species in the rhizosphere orchestrate the recruitment of beneficial bacteria.The EMBO journal · 2026Article
- Spatial microbiome and synthetic community analyses reveal Trinickia sclerotiorum sp. nov. promotes sclerotia mortality of Sclerotinia sclerotiorum.The ISME journal · 2026Article
- Upregulated jasmonate signaling shifts Arabidopsis microbiota interactions and stress adaptations through a positive feedback loop.The ISME journal · 2026Article
- Evolutionary mechanisms underlying bacterial adaptation to the plant environment.FEMS microbiology reviews · 2026Review
- Article
- Synthetic rhizosphere bacterial communities induce systemic resistance to barley powdery mildew without major shifts in the native bacterial community.Frontiers in microbiology · 2026Article
- Improving a Tn7-based luciferase reporter system for promoter activity studies.Microbiology (Reading, England) · 2026Article
- Tissue-specific changes in endophytic bacterial and fungal communities of two pine species associated with pine wilt disease.Frontiers in microbiology · 2026Article
Corrections and comments
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Authors and funding
12 authors at 1 institution in 2 countries.
Funding
Abstract
In healthy plants, the innate immune system contributes to maintenance of microbiota homoeostasis, while disease can be associated with microbiome perturbation or dysbiosis, and enrichment of opportunistic plant pathogens like Xanthomonas. It is currently unclear whether the microbiota change occurs independently of the opportunistic pathogens or is caused by the latter. Here we tested if protein export through the type-2 secretion system (T2SS) by Xanthomonas causes microbiome dysbiosis in Arabidopsis thaliana in immunocompromised plants. We found that Xanthomonas strains secrete a cocktail of plant cell wall-degrading enzymes that promote Xanthomonas growth during infection. Disease severity and leaf tissue degradation were increased in A. thaliana mutants lacking the NADPH oxidase RBOHD. Experiments with gnotobiotic plants, synthetic bacterial communities and wild-type or T2SS-mutant Xanthomonas revealed that virulence and leaf microbiome composition are controlled by the T2SS. Overall, a compromised immune system in plants can enrich opportunistic pathogens, which damage leaf tissues and ultimately cause microbiome dysbiosis by facilitating growth of specific commensal bacteria.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.