ArticleNature neuroscience2024
The logic of recurrent circuits in the primary visual cortex.
Article in Nature neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
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Who cites it
65 citing papers in PubMed.
- Article
- Tuft Dendrite Spikes Are Accompanied by Selective Input From Distinct Functional Networks.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Recurrent synapses between CO2-sensitive olfactory sensory neurons enable robust CO2 detection in Aedes aegypti mosquitoes.PLoS biology · 2026Article
- Probing inter-areal computations with a two-photon holographic mesoscope.Nature neuroscience · 2026Article
- Synaptic Development of Fine Spatial Scale Organization of Neuronal Orientation Tuning in Mouse Primary Visual Cortex.bioRxiv : the preprint server for biology · 2026Article
- Chromatix: a differentiable, GPU-accelerated wave-optics library.Nature methods · 2026Article
- The Importance of Synchrony in the Neural Control of Movement.bioRxiv : the preprint server for biology · 2026Article
- Tuft dendrite spikes are accompanied by selective input from distinct functional networks.bioRxiv : the preprint server for biology · 2026Article
- A computational architecture incorporating shallow brain networks: integrating parallel cortical and subcortical processing.Current research in neurobiology · 2026Article
- Input-dependent directionality of interactions between cortical areas.bioRxiv : the preprint server for biology · 2026Article
- Optogenetic circuit mapping reveals connectivity and synaptic physiology of T-stellate projections from the cochlear nucleus to the auditory midbrain.bioRxiv : the preprint server for biology · 2026Article
- Cell-type-specific parallel pathways in the canonical cortical microcircuit.bioRxiv : the preprint server for biology · 2026Article
- Hominoid-specific calretinin-immunopositivity of the optic radiation (geniculocalcarine tract).Anatomical record (Hoboken, N.J. : 2007) · 2026Article
- Single-Cell Perturbations Reveal Selective Modulation of Causal Connectivity During Decision-Making.bioRxiv : the preprint server for biology · 2026Article
- Millimeter-scale selective amplification in the developing visual cortex.bioRxiv : the preprint server for biology · 2026Article
- Feature-tuned synaptic inputs to somatostatin interneurons drive context-dependent processing.Neuron · 2026Article
- The neural code of perceptual inference.Molecular brain · 2026Review
- Chromatix: a differentiable, GPU-accelerated wave-optics library.bioRxiv : the preprint server for biology · 2026Article
- Article
- Functional reorganization of motor cortex connectivity during learning.bioRxiv : the preprint server for biology · 2026Article
5 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors.
Funding
Abstract
Recurrent cortical activity sculpts visual perception by refining, amplifying or suppressing visual input. However, the rules that govern the influence of recurrent activity remain enigmatic. We used ensemble-specific two-photon optogenetics in the mouse visual cortex to isolate the impact of recurrent activity from external visual input. We found that the spatial arrangement and the visual feature preference of the stimulated ensemble and the neighboring neurons jointly determine the net effect of recurrent activity. Photoactivation of these ensembles drives suppression in all cells beyond 30 µm but uniformly drives activation in closer similarly tuned cells. In nonsimilarly tuned cells, compact, cotuned ensembles drive net suppression, while diffuse, cotuned ensembles drive activation. Computational modeling suggests that highly local recurrent excitatory connectivity and selective convergence onto inhibitory neurons explain these effects. Our findings reveal a straightforward logic in which space and feature preference of cortical ensembles determine their impact on local recurrent activity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.