Evidence map›Paper›PMID 38172335›Full record

ArticleInternational journal of obesity (2005)2024

Change in abdominal obesity after colon cancer surgery - effects of left-sided and right-sided colonic resection.

Younes Kays Mohammed Ali, Troels Gammeltoft Dolin, Janus Damm Nybing, Jakob Lykke, Frederik Hvid Linden, Erik Høgh-Schmidt, Thorkild I A Sørensen, Jesper Frank Christensen, Yousef J W Nielsen, Jim Stenfatt Larsen and 4 more

Open access · hybridAbstract read
In one paragraph

Article in International journal of obesity (2005), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

Younes Kays Mohammed AliDepartment of Endocrinological Research, Copenhagen University Hospital -Amager and Hvidovre, Hvidovre, Denmark.
Troels Gammeltoft DolinDepartment of Medicine, Copenhagen University Hospital - Herlev and Gentofte, Herlev, Denmark.ORCID 0000-0001-6346-3131
Janus Damm NybingDepartment of Radiology, Copenhagen University Hospital - Bispebjerg, Copenhagen, Denmark.
Jakob LykkeDepartment of Surgery, Copenhagen University Hospital - Herlev and Gentofte, Herlev, Denmark.
Frederik Hvid LindenDepartment of Radiology, Copenhagen University Hospital - Bispebjerg, Copenhagen, Denmark.
Erik Høgh-SchmidtDepartment of Radiology, Copenhagen University Hospital - Bispebjerg, Copenhagen, Denmark.
Thorkild I A SørensenNovo Nordisk Foundation Center for Basic Metabolic Research and Department of Public Health, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-4821-430X
Jesper Frank ChristensenCentre for Physical Activity Research, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Yousef J W NielsenDepartment of Radiology, Copenhagen University Hospital - Herlev and Gentofte, Herlev, Denmark.ORCID 0000-0002-5060-1352
Jim Stenfatt LarsenDepartment of Oncology, Copenhagen University Hospital - Herlev and Gentofte, Herlev, Denmark.
Sten MadsbadDepartment of Endocrinological Research, Copenhagen University Hospital -Amager and Hvidovre, Hvidovre, Denmark.
Julia Sidenius JohansenDepartment of Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Maria Saur SvaneDepartment of Endocrinological Research, Copenhagen University Hospital -Amager and Hvidovre, Hvidovre, Denmark.ORCID 0000-0002-7345-4471
Louise Lang LehrskovCentre for Physical Activity Research, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark. louise.lang.lehrskov.01@regionh.dk.ORCID 0000-0002-1947-4252
University of Copenhagen · DKBispebjerg Hospital · DKGentofte Hospital · DKHerlev Hospital · DKHvidovre Hospital · DKUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExcess abdominal visceral adipose tissue (VAT) is associated with metabolic diseases and poor survival in colon cancer (CC). We assessed the impact of different types of CC surgery on changes in abdominal fat depots. MATERIAL AND

methodsComputed tomography (CT)-scans performed preoperative and 3 years after CC surgery were analyzed at L3-level for VAT, subcutaneous adipose tissue (SAT) and total adipose tissue (TAT) areas. We assessed changes in VAT, SAT, TAT and VAT/SAT ratio after 3 years and compared the changes between patients who had undergone left-sided and right-sided colonic resection in the total population and in men and women separately.

resultsA total of 134 patients with stage I-III CC undergoing cancer surgery were included. Patients who had undergone left-sided colonic resection had after 3 years follow-up a 5% (95% CI: 2-9%, p < 0.01) increase in abdominal VAT, a 4% (95% CI: 2-6%, p < 0.001) increase in SAT and a 5% increase (95% CI: 2-7%, p < 0.01) in TAT. Patients who had undergone right-sided colonic resection had no change in VAT, but a 6% (95% CI: 4-9%, p < 0.001) increase in SAT and a 4% (95% CI: 1-7%, p < 0.01) increase in TAT after 3 years. Stratified by sex, only males undergoing left-sided colonic resection had a significant VAT increase of 6% (95% CI: 2-10%, p < 0.01) after 3 years.

conclusionAfter 3 years follow-up survivors of CC accumulated abdominal adipose tissue. Notably, those who underwent left-sided colonic resection had increased VAT and SAT, whereas those who underwent right-sided colonic resection demonstrated solely increased SAT.

Indexed as

Colonic NeoplasmsObesity, AbdominalFemaleHumansIntra-Abdominal FatMaleObesitySubcutaneous FatTomography, X-Ray Computed

Identifiers

PMID38172335
PMCPMC10978490
OpenAlexW4390571868

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.