Evidence map›Paper›PMID 38172192›Full record

ArticleScientific reports2024

Maternal exposure to polyethylene micro- and nanoplastics impairs umbilical blood flow but not fetal growth in pregnant mice.

Jenna Hanrahan, Katherine L Steeves, Drew P Locke, Thomas M O'Brien, Alexandre S Maekawa, Roshanak Amiri, Christopher K Macgowan, Ahmet A Baschat, John C Kingdom, André J Simpson and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Micro and Nanoplastics and Obstetric Outcomes in Humans and Animals: A Systematic Review.International journal of environmental research and public health · 2026
    Pooled it
  2. Review
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  4. Micro-nanoplastic induced cardiovascular disease and dysfunction: a scoping review.Journal of exposure science & environmental epidemiology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Jenna HanrahanDepartment of Chemistry, Memorial University of Newfoundland, Arctic Avenue, St. John's, NL, A1C 5S7, Canada.
Katherine L SteevesDepartment of Chemistry, Memorial University of Newfoundland, Arctic Avenue, St. John's, NL, A1C 5S7, Canada.
Drew P LockeDepartment of Chemistry, Memorial University of Newfoundland, Arctic Avenue, St. John's, NL, A1C 5S7, Canada.
Thomas M O'BrienDepartment of Chemistry, Memorial University of Newfoundland, Arctic Avenue, St. John's, NL, A1C 5S7, Canada.
Alexandre S MaekawaDepartment of Chemistry, Memorial University of Newfoundland, Arctic Avenue, St. John's, NL, A1C 5S7, Canada.
Roshanak AmiriDepartment of Chemistry, Memorial University of Newfoundland, Arctic Avenue, St. John's, NL, A1C 5S7, Canada.
Christopher K MacgowanTranslational Medicine, Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada.
Ahmet A BaschatDepartment of Gynecology and Obstetrics, Johns Hopkins Center for Fetal Therapy, Johns Hopkins University, Baltimore, MD, 21287, USA.
John C KingdomDepartment of Obstetrics and Gynecology, University of Toronto, Toronto, ON, M5G 1E2, Canada.
André J SimpsonEnvironmental NMR Centre and Department of Physical and Environmental Sciences, University of Toronto, Toronto, ON, M1C 1A4, Canada.
Myrna J SimpsonEnvironmental NMR Centre and Department of Physical and Environmental Sciences, University of Toronto, Toronto, ON, M1C 1A4, Canada.
John G SledTranslational Medicine, Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada.
Karl J JobstDepartment of Chemistry, Memorial University of Newfoundland, Arctic Avenue, St. John's, NL, A1C 5S7, Canada.
Lindsay S CahillDepartment of Chemistry, Memorial University of Newfoundland, Arctic Avenue, St. John's, NL, A1C 5S7, Canada. lcahill@mun.ca.
Memorial University of Newfoundland · CAUniversity of Toronto · CAJohns Hopkins Center for Communication Programs · USMount Sinai Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While microplastics have been recently detected in human blood and the placenta, their impact on human health is not well understood. Using a mouse model of environmental exposure during pregnancy, our group has previously reported that exposure to polystyrene micro- and nanoplastics throughout gestation results in fetal growth restriction. While polystyrene is environmentally relevant, polyethylene is the most widely produced plastic and amongst the most commonly detected microplastic in drinking water and human blood. In this study, we investigated the effect of maternal exposure to polyethylene micro- and nanoplastics on fetal growth and placental function. Healthy, pregnant CD-1 dams were divided into three groups: 10

Indexed as

Drinking WaterPlacentaFemaleFetal DevelopmentFetal Growth RetardationHemodynamicsHumansMaternal ExposureMicroplasticsPlasticsPolyethylenePolystyrenesPregnancyPregnancy OutcomeSurface-Active AgentsDrinking WaterMicroplasticsPlasticsPolyethylenePolystyrenesSurface-Active Agents

Identifiers

PMID38172192
PMCPMC10764924
OpenAlexW4390571695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.