Evidence map›Paper›PMID 38172079›Full record

ArticleMolecular pain

Effects of systemic oxytocin administration on ultraviolet B-induced nociceptive hypersensitivity and tactile hyposensitivity in mice.

M Danilo Boada, Silvia Gutierrez, James C Eisenach

Open access · goldAbstract read
In one paragraph

Article in Molecular pain. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.6field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

M Danilo BoadaDepartment of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.ORCID 0000-0002-8973-3010
Silvia GutierrezDepartment of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
James C EisenachDepartment of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.ORCID 0000-0002-9841-0176
Wake Forest University · US

Funding

Pharmacokinetics/Pharmacodynamics CoreP01NS119159 · NINDS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI James Eisenach · 2022 to 2026
$10.4M
NINDS NIH HHS P01 NS119159
6 · The paper itself

Abstract

Ultraviolet B (UVB) radiation induces cutaneous inflammation, leading to thermal and mechanical hypersensitivity. Here, we examine the mechanical properties and profile of tactile and nociceptive peripheral afferents functionally disrupted by this injury and the role of oxytocin (OXT) as a modulator of this disruption. We recorded intracellularly from L4 afferents innervating the irradiated area (5.1 J/cm

Indexed as

NociceptionOxytocinAnimalsMaleMechanoreceptorsMiceMice, Inbred C57BLNociceptorsSkinTouchOxytocinNociceptionoxytocinpainsensitizationultraviolet B radiation

Identifiers

PMID38172079
PMCPMC10846038
OpenAlexW4390563173

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.