Evidence map›Paper›PMID 38171870›Full record

ArticleInternal medicine (Tokyo, Japan)2024

Relapse of Ulcerative Colitis with Immune Thrombocytopenia and Pyoderma Gangrenosum Subsequent to Receiving COVID-19 Vaccination.

Kohei Suzuki, Masato Aizawa, Kana Tamazawa, Kenta Ueda, Jun Wada, Yuki Nakajima, Goro Shibukawa, Shohei Ikeda, Saburo Tsunoda, Kazutomo Togashi

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Kohei SuzukiDepartment of Coloproctology & Gastroenterology, Fukushima Medical University Aizu Medical Center, Japan.
Masato AizawaDepartment of Coloproctology & Gastroenterology, Fukushima Medical University Aizu Medical Center, Japan.
Kana TamazawaDepartment of Coloproctology & Gastroenterology, Fukushima Medical University Aizu Medical Center, Japan.
Kenta UedaDepartment of Coloproctology & Gastroenterology, Fukushima Medical University Aizu Medical Center, Japan.
Jun WadaDepartment of Coloproctology & Gastroenterology, Fukushima Medical University Aizu Medical Center, Japan.
Yuki NakajimaDepartment of Coloproctology & Gastroenterology, Fukushima Medical University Aizu Medical Center, Japan.
Goro ShibukawaDepartment of Coloproctology & Gastroenterology, Fukushima Medical University Aizu Medical Center, Japan.
Shohei IkedaDepartment of Hematology, Fukushima Medical University Aizu Medical Center, Japan.
Saburo TsunodaDepartment of Hematology, Fukushima Medical University Aizu Medical Center, Japan.
Kazutomo TogashiDepartment of Coloproctology & Gastroenterology, Fukushima Medical University Aizu Medical Center, Japan.
Fukushima Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case illustrates the complex interactions of the immune responses after vaccination and highlights their potential connections to various autoimmune conditions. A 22-year-old man with quiescent ulcerative colitis (UC) presented with abdominal pain, rectal bleeding, and thrombocytopenia 7 days after receiving the third coronavirus disease 2019 mRNA vaccination. Laboratory data confirmed the diagnosis of immune thrombocytopenia. High-dose intravenous immunoglobulin administration boosted the patient's platelet count. Simultaneously, colonoscopy revealed that his UC had relapsed. Although salazosulfapyridine briefly improved his symptoms, his stool frequency worsened one week later. The patient also developed pyoderma gangrenosum. Subsequent treatment with infliximab notably improved both pyoderma gangrenosum and UC.

Indexed as

Colitis, UlcerativeCOVID-19COVID-19 VaccinesPurpura, Thrombocytopenic, IdiopathicPyoderma GangrenosumThrombocytopeniaAdultChronic DiseaseHumansMaleRecurrenceYoung AdultCOVID-19 Vaccinesanti-TNF-α antibodyimmune thrombocytopeniainflammatory bowel diseasepyoderma gangrenosumulcerative colitis

Identifiers

PMID38171870
PMCPMC10982002
OpenAlexW4390479961

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.