Evidence map›Paper›PMID 38171869›Full record

ArticleInternal medicine (Tokyo, Japan)2024

Effective Management of Hypertensive Emergencies with Aliskiren Treatment in a Patient before and after Introducing Hemodialysis Secondary to Scleroderma Renal Crisis-like Condition under Corticosteroid Treatment for Sjögren Syndrome-associated Multiple Mononeuropathy.

Osamu Yamazaki, Masataka Murakawa, Fumika Ochiai, Wataru Fujii, Shinichiro Asakawa, Michito Nagura, Shigeyuki Arai, Yoshifuru Tamura, Ryuji Ohashi, Shigeru Shibata and 1 more

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Primary Sjogren syndrome with suspected central nervous system inflammatory involvement.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Osamu YamazakiDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Masataka MurakawaDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Fumika OchiaiDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Wataru FujiiDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Shinichiro AsakawaDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Michito NaguraDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Shigeyuki AraiDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Yoshifuru TamuraDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Ryuji OhashiDepartment of Integrated Diagnostic Pathology, Nippon Medical School, Japan.
Shigeru ShibataDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Yoshihide FujigakiDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A middle-aged woman presented with hypertensive emergency after corticosteroid treatment for Sjögren syndrome-associated multiple mononeuropathy with suspected systemic sclerosis. Hypertensive heart failure with hyperreninemia improved with antihypertensives, including aliskiren; however, she became hemodialysis-dependent. Clinical findings and biopsy-proven thrombotic microangiopathy indicated conditions resembling scleroderma renal crisis (SRC). Severe hypertension and heart failure with hyperreninemia occurred after stopping aliskiren for hypotension due to diverticular bleeding, which improved after the reintroduction of aliskiren. Aliskiren appears to be effective in managing hypertensive heart failure in patients with SRC. Nevertheless, hemodialysis remained necessary in our case, and whether or not aliskiren can restore the renal function is unclear.

Indexed as

AmidesAntihypertensive AgentsFumaratesHypertensionRenal DialysisScleroderma, SystemicSjogren's SyndromeAdrenal Cortex HormonesEmergenciesFemaleHeart FailureHumansHypertensive CrisisMiddle AgedTreatment OutcomeAdrenal Cortex HormonesaliskirenAmidesAntihypertensive AgentsFumaratesaliskirenhyperreninemiahypertensionmultiple mononeuropathyscleroderma renal crisisthrombotic microangiopathy

Identifiers

PMID38171869
PMCPMC11414372

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.