ReviewThe Journal of neuroscience : the official journal of the Society for Neuroscience2024
Cortical Reorganization after Limb Loss: Bridging the Gap between Basic Science and Clinical Recovery.
Review in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 29 citations in OpenAlex.
- Chronic Ankle Instability and Low Back Pain: A Narrative Review With a Conceptual Framework Linking Distal and Proximal Sensorimotor Dysfunction.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026Review
- Functional near-infrared spectroscopy: Systematic mapping of abnormal brain function features in neurological disorders.Neural regeneration research · 2026Article
- Cutting a nerve of the hand alters the organization of digit maps in primary somatosensory cortex.Nature human behaviour · 2026Article
- The association between quality of life, anxiety and depression, and residual limb and phantom limb pain in war-related amputees: a year-long observational study.EClinicalMedicine · 2026Article
- The Effect of a Fully Immersive Virtual Reality Training Program on Walking Parameters in People With Unilateral Below-Knee Amputation: An Experimental and a Single-Subject Study.Health science reports · 2026Article
- From Amputation to Persistent Pain: A Review of Molecular and Cellular Processes in Phantom Limb Pain.International journal of molecular sciences · 2026Review
- Post-Critical Period Transcriptional and Physiological Adaptations of Primary Sensory Cortex after Sensory Loss.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Perceptual Design and Evaluation of a Forearm-Based Vibrotactile Interface for Transfemoral Prosthetic Feedback.Biomimetics (Basel, Switzerland) · 2026Article
- Peer mentorship for physically injured veterans in healthcare settings during ongoing military conflict: benefits and barriers.Frontiers in public health · 2026Article
- The Effect of Motor Imagery Ability on Function and Proprioception in Myoelectric Prosthesis Users: Protocol for a Cross-Sectional Study.JMIR research protocols · 2025Article
- Conserved small RNA networks link inflammation to pain signaling in mice and men.Translational psychiatry · 2025Article
- Stable cortical body maps before and after arm amputation.Nature neuroscience · 2025Article
- From nociception in aneural animals to human suffering: toward a comparative biology of pain.The Journal of experimental biology · 2025Review
- Vestibular Versus Cochlear Stimulation on the Relief of Phantom Pain After Traumatic Finger Amputation.Biomedicines · 2025Article
- Reactivated thalamocortical plasticity alters neural activity in sensory-motor cortex during post-critical period.Progress in neurobiology · 2025Article
- Behavioral adaptations after unilateral whisker denervation.Behavioural brain research · 2025Article
- Neurophysiological Markers of Adaptation and Compensation Following Lower Limb Amputation: An Analysis of EEG Oscillations and Clinical Predictors from the DEFINE Cohort Study.Neurology international · 2025Article
- Multimodal Approaches for Pain Management and Improving Functional Outcomes Following Amputation.Journal of orthopaedics and sports medicine · 2025Article
- Cerebellar functional connectivity alteration in individuals with lower limb amputation.PloS one · 2025Article
- Changes in hemispheric dominance following targeted muscle reinnervation: a case study.Frontiers in human neuroscience · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
Despite the increasing incidence and prevalence of amputation across the globe, individuals with acquired limb loss continue to struggle with functional recovery and chronic pain. A more complete understanding of the motor and sensory remodeling of the peripheral and central nervous system that occurs postamputation may help advance clinical interventions to improve the quality of life for individuals with acquired limb loss. The purpose of this article is to first provide background clinical context on individuals with acquired limb loss and then to provide a comprehensive review of the known motor and sensory neural adaptations from both animal models and human clinical trials. Finally, the article bridges the gap between basic science researchers and clinicians that treat individuals with limb loss by explaining how current clinical treatments may restore function and modulate phantom limb pain using the underlying neural adaptations described above. This review should encourage the further development of novel treatments with known neurological targets to improve the recovery of individuals postamputation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.