ReviewKorean journal of anesthesiology2024
Association of preoperative blood glucose level with delirium after non-cardiac surgery in diabetic patients.
Review in Korean journal of anesthesiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 18 citations in OpenAlex.
- Effect of preoperative oral carbohydrate on postoperative delirium in elderly patients undergoing lower extremity orthopedic surgery: a prospective randomized trial.Journal of orthopaedic surgery and research · 2025Trial
- Association between the preoperative stress hyperglycemia ratio and postoperative delirium in older adults undergoing non-cardiac surgery: a retrospective cohort study.European geriatric medicine · 2026Article
- Association between stress hyperglycemia ratio and cognitive function in older patients with diabetes or prediabetes: a cross-sectional study from the NHANES.Endocrine journal · 2026Article
- Associations between polygenic risk scores for Alzheimer's disease and postoperative delirium risk.Journal of Alzheimer's disease : JAD · 2026Article
- Association between hemoglobin glycation index and delirium after gastric surgery: Based upon the MIMIC-IV.Medicine · 2026Article
- Multi-omics analysis reveals sevoflurane exacerbates cognitive impairment in diabetic mice by disrupting lipid metabolism.Scientific reports · 2026Article
- Article
- Diabetes and postoperative cognitive dysfunction and delirium in adults: mechanisms, biomarkers, and clinical management.Frontiers in endocrinology · 2026Review
- Association between stress hyperglycemia ratio and delirium risk in elderly surgical patients: a retrospective cohort study.BMC geriatrics · 2025Article
- Glycated Hemoglobin as a Predictor of Postoperative Delirium in Diabetic Patients Undergoing Noncardiac Surgery: A Retrospective Study.Medicina (Kaunas, Lithuania) · 2025Article
- The impact of perioperative hyperglycemia on postoperative cognitive function: A comprehensive review.IBRO neuroscience reports · 2025Review
- Establishment and validation of a nomogram of postoperative delirium in patients undergoing cardiac surgery: a retrospective study of MIMIC-IV.BMC cardiovascular disorders · 2025Article
- The Role of Stress Hyperglycemia on Delirium Onset.Journal of clinical medicine · 2025Review
- Cardiovascular health score and its association with postoperative delirium: evidence from the Kailuan study.Frontiers in medicine · 2025Article
- Association of triglyceride-glucose index and delirium in patients with sepsis: a retrospective study.Lipids in health and disease · 2024Article
- Predictors and indicators.Korean journal of anesthesiology · 2024Article
- Optimization of the cardiac delirium index by including age, decrease in butyrylcholinesterase actitivity, preoperative HbA1c, and postoperative hemoglobin levels: results of a secondary analysis of a prospective observational study.Frontiers in cardiovascular medicine · 2024Article
- Association of blood glucose change with postoperative delirium after coronary artery bypass grafting in patients with diabetes mellitus: a study of the MIMIC-IV database.Frontiers in endocrinology · 2024Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHyperglycemia has shown a negative association with cognitive dysfunction. We analyzed patients with high preoperative blood glucose level and hemoglobin A1c (HbA1c) level to determine the prevalence of postoperative delirium.
methodsWe reviewed a database of 23,532 patients with diabetes who underwent non-cardiac surgery. Acute hyperglycemia was defined as fasting blood glucose > 140 mg/dl or random glucose > 180 mg/dl within 24 h before surgery. Chronic hyperglycemia was defined as HbA1c level above 6.5% within three months before surgery. The incidence of delirium was compared according to the presence of acute and chronic hyperglycemia.
resultsOf the 23,532 diabetic patients, 21,585 had available preoperative blood glucose level within 24 h before surgery, and 18,452 patients reported levels indicating acute hyperglycemia. Of the 8,927 patients with available HbA1c level within three months before surgery, 5,522 had levels indicating chronic hyperglycemia. After adjustment with inverse probability weighting, acute hyperglycemia was related to higher incidence of delirium (hazard ratio: 1.33, 95% CI [1.10,1.62], P = 0.004 for delirium) compared with controls without acute hyperglycemia. On the other hand, chronic hyperglycemia did not correlate with postoperative delirium.
conclusionsPreoperative acute hyperglycemia was associated with postoperative delirium, whereas chronic hyperglycemia was not significantly associated with postoperative delirium. Irrespective of chronic hyperglycemia, acute glycemic control in surgical patients could be crucial for preventing postoperative delirium.
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