Evidence map›Paper›PMID 38171286›Full record

ArticleNeurospine2023

Therapeutic Prediction of Osteoporotic Vertebral Compression Fracture Using the AO Spine-DGOU Osteoporotic Fracture Classification and Classification-Based Score: A Single-Center Retrospective Observational Study.

Koki Mitani, Toshiyuki Takahashi, Shinya Tokunaga, Tomoo Inoue, Ryo Kanematsu, Manabu Minami, Junya Hanakita

Open access · diamondAbstract read
In one paragraph

Article in Neurospine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 15 citations in OpenAlex.

  1. Osteoporotic thoracolumbar fractures: age-modified Osteoporotic Fracture-based treatment decisions and length of hospital stay in elderly patients - a prospective single-centre cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  2. Validation of the AO Spine Osteoporotic Fracture Classification-effect of geographical region on reliability and reproducibility.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
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  5. OF-score for osteoporotic thoracolumbar fractures- which parameter is decisive for the therapy decision? - a prospective multicentric cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Koki MitaniSpinal Disorders Center, Fujieda Heisei Memorial Hospital, Fujieda, Japan.
Toshiyuki TakahashiSpinal Disorders Center, Fujieda Heisei Memorial Hospital, Fujieda, Japan.
Shinya TokunagaDepartment of Neurosurgery, Shizuoka General Hospital, Shizuoka, Japan.
Tomoo InoueDepartment of Neurosurgery, Saitama Red Cross Hospital, Saitama, Japan.
Ryo KanematsuSpinal Disorders Center, Fujieda Heisei Memorial Hospital, Fujieda, Japan.
Manabu MinamiSpinal Disorders Center, Fujieda Heisei Memorial Hospital, Fujieda, Japan.
Junya HanakitaSpinal Disorders Center, Fujieda Heisei Memorial Hospital, Fujieda, Japan.
Fujieda Municipal General Hospital · JPSaitama Red Cross Hospital · JPShizuoka General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe treatment of osteoporotic vertebral compression fractures (OVCFs) is based on their severity; however, an efficient prediction tool is lacking. We aimed to evaluate the validity of the osteoporotic fracture classification (OF classification) and scoring system (OF score) in predicting the treatment strategy for patients with OVCF, defined according to the Japanese criteria.

methodsWe retrospectively investigated 487 consecutive patients diagnosed with vertebral body fractures between January 2018 and December 2022. Only patients with their fresh vertebral fracture episode during the study period were included. Patients were classified into 3 groups: conservative treatment, balloon kyphoplasty (BKP), and open surgery. OF classification and OF scores were assessed for each patient.

resultsA total of 237 patients with OVCF were included. There were 127, 81, and 29 patients in the conservative, BKP, and open surgery groups, respectively. The OF score was significantly higher in the BKP and open surgery groups than in the conservative group (p < 0.001). Multivariate logistic regression analysis showed that antiosteoporotic drug use, OF classification, progressive deformity, neurological symptoms and mobilization were independent risk factors for operative treatment (all p < 0.001). Receiver operating characteristic analysis showed that the cutoff OF score for operative indication was 5.5, with a sensitivity of 91.9%, specificity of 56.5%, and area under the curve of 0.820 (95% confidence interval, 0.769-0.871).

conclusionThe OF score identified patients who required operative treatment with a high degree of accuracy. This is especially important for ruling out patients who definitely require operative treatment.

Indexed as

OF classificationOF scoreOsteoporosisOsteoporotic fractureRetrospective studyVertebral compression fracture

Identifiers

PMID38171286
PMCPMC10762420
OpenAlexW4390296004

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.