ArticleNeurospine2023
Comparative Efficacy of Surgical Interventions for Osteoporotic Vertebral Compression Fractures: A Systematic Review and Network Meta-analysis.
Article in Neurospine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 17 citations in OpenAlex.
- Clinical Outcomes of Percutaneous Vertebroplasty and Conservative Management in Patients With Osteoporotic Vertebral Compression Fractures.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Vertebral augmentation procedures for osteoporotic vertebral compression fractures: a network meta-analysis of randomized controlled trials.Neurosurgical review · 2026Review
- The bisegmental Cobb angle in osteoporotic spine fractures: Does it influence treatment decision or functional outcome?Brain & spine · 2026Article
- Predicting long-term clinical mortality of elderly patients with vertebral compression fractures.Frontiers in medicine · 2026Article
- Influence of thoracolumbar kyphotic Cobb angle on prognosis after PKP surgery.Scientific reports · 2025Article
- The Use of Polymethylmethacrylate Cement in Percutaneous Vertebroplasty Versus Conservative Management: How to Treat Osteoporotic Vertebral Compression Fractures.Medicina (Kaunas, Lithuania) · 2025Observational
- Minimally Invasive Treatment Using Biportal Endoscopic Decompression with Vertebroplasty for Osteoporotic Vertebral Compression Fractures in Older Adult Patients.Clinics in orthopedic surgery · 2025Article
- Prophylactic Antibiotics in Vertebroplasty and Kyphoplasty: A Nationwide Analysis of Infection Rates and Antibiotic Use in South Korea.Antibiotics (Basel, Switzerland) · 2025Article
- Interleukin Concentrations in Bone Marrow Fluid and MRI Prognostic Findings in Osteoporotic Vertebral Fractures.Cureus · 2025Article
- Review
- Percutaneous Vertebroplasty and Balloon Kyphoplasty for Painful Osteoporotic Vertebral Compression Fractures: A Health Technology Assessment.Ontario health technology assessment series · 2025Article
- Validity and reliability of the osteoporotic fracture treatment score (OF score) and outcomes across various treatments in osteoporosis vertebral compression fracture patients.Journal of orthopaedic surgery and research · 2024Article
- Clinical significance of modified unilateral puncture percutaneous vertebroplasty guided by 3D- printed guides in the treatment of osteoporotic vertebral compression fractures: a retrospective study.BMC musculoskeletal disorders · 2024Article
- Clinical Oversight and Delayed Diagnosis of a Pathological Compression Fracture Causing Paraplegia.Cureus · 2024Article
- Commentary on "Deep Learning-Assisted Quantitative Measurement of Thoracolumbar Fracture Features on Lateral Radiographs".Neurospine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe aimed to comprehensively compare surgical methods for osteoporotic vertebral compression fracture (OVCF) using systematic review and network meta-analysis to understand their effectiveness and outcomes, as current research provides limited overviews.
methodsWe followed PRISMA (preferred reporting items for systematic reviews and meta-analyses) guidelines, preregistering our protocol with PROSPERO. We analyzed Englishpublished randomized controlled trials (RCTs) on adults with OVCFs that evaluated pain intensity or functionality using tools like visual analogue scale (VAS) or Oswestry Disability Index (ODI). Exclusions included non-RCTs, malignancy-related fractures, and certain interventions. Using the RoB 2 tool, we assessed bias and visualized results with Robvis. Our primary outcome was pain intensity, with secondary outcomes including disability, new fractures, and cement leakage. Results were synthesized using Stata/MP.
resultsThirty-four RCTs from 10 countries, totaling 4,384 patients, were analyzed. Shortterm VAS indicated kyphoplasty with facet joint injection (KIJ) as the top treatment at 87.7%, while unipedicular kyphoplasty (UKP) led to long-term at 74.9%. Short-term ODI favored vertebroplasty with facet joint injection (VIJ) at 98.4%, with kyphoplasty (KP) leading longterm at 66.0%. All surgical techniques were superior to conservative treatment. Vertebral augmentation devices reported the fewest new fractures and curved vertebroplasty had the least cement leakage. SUCRA (surface under the cumulative ranking) analyses suggested UKP and VIJ as top choices for postoperative pain relief, with VIJ excelling in postoperative disability improvement.
conclusionOur analysis evaluates 12 OVCF interventions, underscoring KIJ for short-term pain relief and VIJ and UKP for long-term efficacy. Notably, VIJ stands out in disability outcomes, emphasizing the need for comprehensive OVCF management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.