ArticleScience advances2024
The chemokine receptor CXCR3 promotes CD8
Open access · goldAbstract read
In one paragraph
Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 18 citations in OpenAlex.
- TFAM Dependent Mitochondrial Fitness Limits CD8bioRxiv : the preprint server for biology · 2026Article
- Mucosal immunity: mechanism and application in cancer immunotherapy.Journal of hematology & oncology · 2026Review
- Activated immune cells present a lung interstitial-to-airway/alveolar cross-compartment sharing pattern in severe pneumonia.Clinical and translational medicine · 2026Article
- A non-canonical role ofbioRxiv : the preprint server for biology · 2026Article
- The role of T cells in influenza infection and vaccination.Virologica Sinica · 2026Review
- High expression of interleukin-18 receptor alpha correlates with severe respiratory viral disease and defines T cells with reduced cytotoxic signatures.Nature communications · 2025Article
- NF-κB driven inflammation mediates loss of upper airway epithelial tolerance tobioRxiv : the preprint server for biology · 2025Article
- A Dapl1Science advances · 2025Article
- Mendelian randomization analysis reveals causal relationship between allergic diseases and influenza.The World Allergy Organization journal · 2025Article
- Distinct type 1 immune networks underlie the severity of restrictive lung disease after COVID-19.Nature immunology · 2025Article
- Functional regulation of cytotoxic T cells by gut microbial metabolites.Gut microbes reports · 2025Article
- Synthetic DNA co-immunization with vaccine-aligned common consensus nucleoprotein and hemagglutinin protects mice against lethal influenza infection with a single immunization.Frontiers in immunology · 2025Article
- Platelets as a potential new immune coordinator in T cell-mediated aplastic anemia.Frontiers in oncology · 2025Review
- Chemokines Signature and T Cell Dynamics in Leishmaniasis: Molecular insight and therapeutic application.Expert reviews in molecular medicine · 2024Review
- Immune responses drive chorioretinitis and retinal pathology after neonatal CMV infection.Science advances · 2024Article
- A Prime-Boost Vaccination Approach Induces Lung Resident Memory CD8+ T Cells Derived from Central Memory T Cells That Prevent Tumor Lung Metastasis.Cancer research · 2024Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 5 institutions in 2 countries.
Kai GuoDepartment of Neurology, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0002-4651-781X
Dan J K YomboDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND 58202, USA.ORCID 0000-0002-1469-503X
Zhihan WangDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND 58202, USA.ORCID 0000-0002-3617-477X
Zahrasadat NavaeiseddighiDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL 32610, USA.
Jintao XuResearch Service, Ann Arbor VA Health System, Department of Veterans Affairs Health System, Ann Arbor, MI 48109, USA.ORCID 0000-0002-9946-8601
Taylor SchmitDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND 58202, USA.ORCID 0000-0002-7637-1110
Nassem AhamadDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL 32610, USA.
Jitendra TripathiDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND 58202, USA.ORCID 0000-0001-9246-8388
Bony De KumarDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND 58202, USA.
Ramkumar MathurDepartment of Geriatrics, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND 58202, USA.
Junguk HurDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND 58202, USA.ORCID 0000-0002-0736-2149
Jie SunCarter Immunology Center, University of Virginia, Charlottesville, VA 22908, USA.ORCID 0000-0002-2347-4511
Michal A OlszewskiResearch Service, Ann Arbor VA Health System, Department of Veterans Affairs Health System, Ann Arbor, MI 48109, USA.ORCID 0000-0001-7474-0843
Nadeem KhanDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND 58202, USA.ORCID 0000-0001-7870-4989
University of North Dakota · USUniversity of Florida · USVA Ann Arbor Healthcare System · USCarter Center · USUniversity of Michigan · US
Funding
Yersina perstis interactions with macrophagesP20GM113123 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI HUR, JUNGUK · 2016 to 2025
$19.9MPathogenic role of IL-17 response in Streptococcus pneumoniae nasopharyngeal pathogenesis during an influenza virus co-infectionR01AI143741 · NIAID · UNIVERSITY OF NORTH DAKOTA · PI KHAN, NADEEM · 2020 to 2024
$1.9MUtilization of the adjuvant effect of CRM197 protein to develop a trivalentprotein-vaccine against Streptococcus pneumoniae infectionsR21AI151522 · NIAID · UNIVERSITY OF NORTH DAKOTA · PI KHAN, NADEEM · 2021 to 2022
$402kModulation of Pulmonary Defenses in Pathobiology of Chronic InfectionsI01BX000656 · VA · VETERANS HEALTH ADMINISTRATION · PI OLSZEWSKI, MICHAL A · 2011 to 2025
–Offsetting CNS inflammatory damage with anti-CXCR3 antibody immunotherapyI21BX006349 · VA · VETERANS HEALTH ADMINISTRATION · PI OLSZEWSKI, MICHAL A · 2024 to 2025
–BLRD Research Career Scientist Award ApplicationIK6BX005966 · VA · VETERANS HEALTH ADMINISTRATION · PI OLSZEWSKI, MICHAL A · 2022 to 2025
–BLRD VA I01 BX000656BLRD VA I21 BX006349BLRD VA IK6 BX005966NIAID NIH HHS R01 AI143741NIAID NIH HHS R21 AI151522NIGMS NIH HHS P20 GM113123
Abstract
The dual role of CD8
Indexed as
Influenza, HumanLung InjuryAnimalsCD8-Positive T-LymphocytesHumansLungMiceMice, Inbred C57BLMice, KnockoutReceptors, ChemokineReceptors, CXCR3Cxcr3 protein, mouseReceptors, ChemokineReceptors, CXCR3
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.