Evidence map›Paper›PMID 38170619›Full record

ReviewChemical Society reviews2024

Therapeutic synthetic and natural materials for immunoengineering.

Anna Slezak, Kevin Chang, Samir Hossainy, Aslan Mansurov, Stuart J Rowan, Jeffrey A Hubbell, Mustafa O Guler

Abstract readReview
In one paragraph

Review in Chemical Society reviews, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
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  8. Review
  9. Peptide-Based Biomaterials as a Promising Tool for Cancer Radiotherapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Nanoparticle-based Gene Therapy for Neurodegenerative Disorders.Mini reviews in medicinal chemistry · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anna SlezakThe Pritzker School of Molecular Engineering, The University of Chicago, Chicago, IL, 60637, USA. jhubbell@uchicago.edu.
Kevin ChangThe Pritzker School of Molecular Engineering, The University of Chicago, Chicago, IL, 60637, USA. jhubbell@uchicago.edu.ORCID http://orcid.org/0000-0001-6895-8950
Samir HossainyThe Pritzker School of Molecular Engineering, The University of Chicago, Chicago, IL, 60637, USA. jhubbell@uchicago.edu.
Aslan MansurovThe Pritzker School of Molecular Engineering, The University of Chicago, Chicago, IL, 60637, USA. jhubbell@uchicago.edu.
Stuart J RowanThe Pritzker School of Molecular Engineering, The University of Chicago, Chicago, IL, 60637, USA. jhubbell@uchicago.edu.ORCID http://orcid.org/0000-0001-8176-0594
Jeffrey A HubbellThe Pritzker School of Molecular Engineering, The University of Chicago, Chicago, IL, 60637, USA. jhubbell@uchicago.edu.
Mustafa O GulerThe Pritzker School of Molecular Engineering, The University of Chicago, Chicago, IL, 60637, USA. jhubbell@uchicago.edu.ORCID http://orcid.org/0000-0003-1168-202X

Funding

Medical Scientist National Research Service AwardT32GM150375 · NIGMS · UNIVERSITY OF CHICAGO · PI Raghavendra G Mirmira · 2023 to 2026
$5.5M
NIGMS NIH HHS T32 GM150375
6 · The paper itself

Abstract

Immunoengineering is a rapidly evolving field that has been driving innovations in manipulating immune system for new treatment tools and methods. The need for materials for immunoengineering applications has gained significant attention in recent years due to the growing demand for effective therapies that can target and regulate the immune system. Biologics and biomaterials are emerging as promising tools for controlling immune responses, and a wide variety of materials, including proteins, polymers, nanoparticles, and hydrogels, are being developed for this purpose. In this review article, we explore the different types of materials used in immunoengineering applications, their properties and design principles, and highlight the latest therapeutic materials advancements. Recent works in adjuvants, vaccines, immune tolerance, immunotherapy, and tissue models for immunoengineering studies are discussed.

Indexed as

ImmunotherapyVaccinesBiocompatible MaterialsProteinsBiocompatible MaterialsProteinsVaccines

Identifiers

PMID38170619
PMCPMC11557218

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.