Evidence map›Paper›PMID 38170572›Full record

ArticleMolecular biology of the cell2024

The ubiquitin ligases Cbl and Cbl-b regulate macrophage growth by controlling CSF-1R import into macropinosomes.

Lu Huang, Natalie W Thiex, Jieqiong Lou, Gulzar Ahmad, Wei An, Shalini T Low-Nam, Jason G Kerkvliet, Hamid Band, Adam D Hoppe

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular biology of the cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Lu HuangDepartment of Chemistry and Biochemistry, South Dakota State University, Brookings, SD 57007.
Natalie W ThiexDepartment of Biology and Microbiology, South Dakota State University, Brookings, SD 57007.
Jieqiong LouDepartment of Chemistry and Biochemistry, South Dakota State University, Brookings, SD 57007.
Gulzar AhmadEppley Institute for Research in Cancer and Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198.
Wei AnEppley Institute for Research in Cancer and Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198.
Shalini T Low-NamDepartment of Chemistry and Biochemistry, South Dakota State University, Brookings, SD 57007.
Jason G KerkvlietDepartment of Chemistry and Biochemistry, South Dakota State University, Brookings, SD 57007.
Hamid BandEppley Institute for Research in Cancer and Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198.
Adam D HoppeDepartment of Chemistry and Biochemistry, South Dakota State University, Brookings, SD 57007.
South Dakota State University · USUniversity of Nebraska Medical Center · US

Funding

Transcriptome & Networks Analysis CoreP20GM135008 · NIGMS · SOUTH DAKOTA STATE UNIVERSITY · PI Adam David Hoppe · 2022 to 2026
$13.5M
The immune regulation of macrophage antibody dependent cellular phagocytosisU01AI148153 · NIAID · SOUTH DAKOTA STATE UNIVERSITY · PI HOPPE, ADAM DAVID · 2020 to 2024
$1.9M
NIAID NIH HHS U01 AI148153NIGMS NIH HHS P20 GM135008
6 · The paper itself

Abstract

The ubiquitination of transmembrane receptors regulates endocytosis, intracellular traffic, and signal transduction. Bone marrow-derived macrophages from myeloid Cbl

Indexed as

Receptor, Macrophage Colony-Stimulating FactorUbiquitinAnimalsMacrophage Colony-Stimulating FactorMacrophagesMiceProto-Oncogene Proteins c-cblReceptor Protein-Tyrosine KinasesUbiquitin-Protein LigasesMacrophage Colony-Stimulating FactorProto-Oncogene Proteins c-cblReceptor, Macrophage Colony-Stimulating FactorReceptor Protein-Tyrosine KinasesUbiquitinUbiquitin-Protein Ligases

Identifiers

PMID38170572
PMCPMC10916879
OpenAlexW4390535486

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.