Evidence map›Paper›PMID 38170398›Full record

ArticleJournal of epidemiology and global health2024

Global Cervical Cancer Incidence by Histological Subtype and Implications for Screening Methods.

Minmin Wang, Kepei Huang, Martin C S Wong, Junjie Huang, Yinzi Jin, Zhi-Jie Zheng

Open access · goldAbstract read
In one paragraph

Article in Journal of epidemiology and global health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
20.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
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  15. medRxiv : the preprint server for health sciences · 2026
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  18. Conclusions Are in Part Inexplicable.Deutsches Arzteblatt international · 2026
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  19. In Reply.Deutsches Arzteblatt international · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Minmin WangDepartment of Global Health, School of Public Health, Peking University, 38 Xue Yuan Road, Haidian District, Beijing, 100191, China.
Kepei HuangDepartment of Global Health, School of Public Health, Peking University, 38 Xue Yuan Road, Haidian District, Beijing, 100191, China.
Martin C S WongThe Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR, China.
Junjie HuangThe Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR, China.
Yinzi JinDepartment of Global Health, School of Public Health, Peking University, 38 Xue Yuan Road, Haidian District, Beijing, 100191, China. yzjin@bjmu.edu.cn.ORCID http://orcid.org/0000-0003-0634-3955
Zhi-Jie ZhengDepartment of Global Health, School of Public Health, Peking University, 38 Xue Yuan Road, Haidian District, Beijing, 100191, China.
Peking University · CNChinese University of Hong Kong · HK

Funding

Bill and Melinda Gates Foundation INV-0045085
6 · The paper itself

Abstract

backgroundCervical cancer is a major global health concern, disproportionately affecting women in developing countries. Cervical cancer has two primary subtypes, squamous cell carcinoma (SCC) and adenocarcinoma (AC), each with distinct characteristics and screening effectiveness. In this study, we aimed to estimate the global incidence of cervical cancer according to histological subtype to inform prevention strategies.

methodsUsing data from population-based cancer registries, we computed the rates of SCC, AC, and other specified histology among all cervical cancer cases by country and by 5-year age group. Proportions were subsequently applied to the estimated number of cervical cancer cases from the Global Cancer Observatory 2020. Age-standardized incidence rates were calculated.

resultsSCC accounted for 82.72% of global cervical cancer cases, with AC contributing 12.18%. The highest SCC incidence was in Sub-Saharan Africa (29.79 per 100,000 population). The AC incidence was highest in South-Eastern Asia (3.67 per 100,000 population). Age-specific trends showed SCC peaking at approximately age 55 years and AC plateauing after age 45 years.

conclusionsThis study provided a comprehensive estimate of cervical cancer incidence by histological subtype. SCC remained the dominant subtype globally, whereas the incidence of AC varied across regions. These findings highlighted the need for tailored prevention strategies, especially testing for human papillomavirus to detect AC in high burden areas.

Indexed as

AdenocarcinomaCarcinoma, Squamous CellEarly Detection of CancerGlobal HealthUterine Cervical NeoplasmsAdolescentAdultAgedFemaleHumansIncidenceMiddle AgedRegistriesYoung AdultAdenocarcinomaCervical cancer screeningHistological subtypeSquamous cell carcinoma

Identifiers

PMID38170398
PMCPMC11043316
OpenAlexW4390570789

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.