Evidence map›Paper›PMID 38170277›Full record

ArticleMolecular biology reports2024

Preparation of biogenic silver chloride nanoparticles from microalgae Spirulina Platensis extract: anticancer properties in MDA-MB231 breast cancer cells.

Mahsa Afzali, Seyed Ataollah Sadat Shandiz, Zahra Keshtmand

Abstract read
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In one paragraph

Article in Molecular biology reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. The Selective in vitro Cytotoxicity ofInternational journal of nanomedicine · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mahsa AfzaliDepartment of Biology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
Seyed Ataollah Sadat ShandizDepartment of Biology, Central Tehran Branch, Islamic Azad University, Tehran, Iran. Ata.sadatshandiz@iauctb.ac.ir.ORCID http://orcid.org/0000-0002-5053-0507
Zahra KeshtmandDepartment of Biology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
Islamic Azad University Central Tehran Branch · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast carcinoma is the second leading cause of cancer related-deaths among women. Given its high incidence and mortality rates, searching for innovative treatments represents a formidable challenge within the medical and pharmaceutical industries. This study delves into the preparation, characterization, and anticancer properties of silver chloride nanoparticles (AgCLNPs) as a novel therapeutic approach for breast cancer cells, employing a biological synthesis method.

methodsThis investigation, utilized spirulina platensis extract to synthesize silver chloride nanoparticles (AgCLNPs-SP). The formation, size, and structure of the nanoparticles were characterized by Transmission Electron Microscopy (TEM), Scanning Electron Microscope (SEM), X-ray crystallography (XRD), and Energy-dispersive X-ray spectroscopy (EDS) analysis. Additionally, the apoptotic and anticancer properties of AgCLNPs-SP were thoroughly examined.

resultsThe results, revealed AgCLNPs-SP to exhibit a spherical, morphology with a size range of 40-70 nm, primarily silver and chlorine. The dose-dependent response of AgCLNP-SP against MDA-MB231 cells was ascertained using the MTT Assay, with an IC

conclusionsIn conclusion, the results suggest that AgCLNPs-SP may be a promising agent for treating breast cancer.

Indexed as

Breast NeoplasmsMetal NanoparticlesMicroalgaeChloridesFemaleHumansMCF-7 CellsPlant ExtractsSilver CompoundsSpirulinaChloridesPlant Extractssilver chlorideSilver CompoundsBreast cancerFlow cytometryMetallic nanoparticlesReactive oxygen speciesSpirulina platensis

Identifiers

PMID38170277
OpenAlexW4390546445

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.