Evidence map›Paper›PMID 38170159›Full record

ArticleOncoimmunology2024

Interferon regulatory factor 4 plays a pivotal role in the development of aGVHD-associated colitis.

Jochen T Frueh, Julia Campe, Daniele Yumi Sunaga-Franze, Nikita A Verheyden, Sakhila Ghimire, Elisabeth Meedt, Denise Haslinger, Sabine Harenkamp, Daniel Staudenraus, Sascha Sauer and 9 more

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 1 country.

Jochen T FruehDepartment of Pediatrics, Experimental Immunology and Cell Therapy, Goethe University Frankfurt, Frankfurt am Main, Germany.
Julia CampeDepartment of Pediatrics, Experimental Immunology and Cell Therapy, Goethe University Frankfurt, Frankfurt am Main, Germany.
Daniele Yumi Sunaga-FranzeGenomics Platform, Max Delbrueck Center for Molecular Medicine, Berlin Institute of Health, Berlin, Germany.
Nikita A VerheydenInstitute for Molecular Medicine, University Hospital, Goethe University Frankfurt, Frankfurt, Germany.
Sakhila GhimireHematology and Oncology Department, Medical Clinic 3, University Hospital Regensburg, Regensburg, Germany.
Elisabeth MeedtHematology and Oncology Department, Medical Clinic 3, University Hospital Regensburg, Regensburg, Germany.
Denise HaslingerDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Sabine HarenkampGerman Red Cross Blood Service BaWüHe, Frankfurt am Main, Germany.
Daniel StaudenrausInstitute for Microbiology, Philipps University, Marburg, Germany.
Sascha SauerGenomics Platform, Max Delbrueck Center for Molecular Medicine, Berlin Institute of Health, Berlin, Germany.
Andreas KreftInstitute of Pathology, University Medical Center Mainz, Mainz, Germany.
Ralf SchubertDepartment of Pediatric Medicine, Division of Pneumology, Allergology, Infectious diseaes und Gastroenterology. Frankfurt am Main, Goethe University Frankfurt, Frankfurt, Germany.
Michael LohoffInstitute for Microbiology, Philipps University, Marburg, Germany.
Andreas KruegerInstitute for Molecular Medicine, University Hospital, Goethe University Frankfurt, Frankfurt, Germany.
Halvard BonigGerman Red Cross Blood Service BaWüHe, Frankfurt am Main, Germany.
Andreas G ChiocchettiDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Robert ZeiserDepartment of Internal Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Ernst HollerHematology and Oncology Department, Medical Clinic 3, University Hospital Regensburg, Regensburg, Germany.
Evelyn UllrichDepartment of Pediatrics, Experimental Immunology and Cell Therapy, Goethe University Frankfurt, Frankfurt am Main, Germany.ORCID 0000-0001-8530-1192
Goethe University Frankfurt · DEUniversity Hospital Regensburg · DEMax Delbrück Center · DEPhilipps University of Marburg · DEGerman Red Cross · DEJohannes Gutenberg University Mainz · DEUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interferon regulatory factor 4 (IRF4) is a master transcription factor that regulates T helper cell (Th) differentiation. It interacts with the Basic leucine zipper transcription factor, ATF-like (BATF), depletion of which in CD4

Indexed as

ColitisGraft vs Host DiseaseAnimalsBasic-Leucine Zipper Transcription FactorsHumansInterferon Regulatory FactorsMiceT-Lymphocytes, RegulatoryBasic-Leucine Zipper Transcription FactorsInterferon Regulatory FactorsAcute GVHDBACH2IRF4T helper cells

Identifiers

PMID38170159
PMCPMC10761041
OpenAlexW4390342547

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.