Evidence map›Paper›PMID 38170110›Full record

ArticleProceedings of the ... IEEE/RSJ International Conference on Intelligent Robots and Systems. IEEE/RSJ International Conference on Intelligent Robots and Systems

A Novel Wax Based Piezo Actuator for Autonomous Deep Anterior Lamellar Keratoplasty (Piezo-DALK).

J D Opfermann, M Barbic, M Khrenov, S Guo, N R Sarfaraz, J U Kang, A Krieger

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the ... IEEE/RSJ International Conference on Intelligent Robots and Systems. IEEE/RSJ International Conference on Intelligent Robots and Systems. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

J D OpfermannDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, MD 21211 USA.
M BarbicTech4Health Institute, NYU School of Medicine, New York, NY 10016 USA.
M KhrenovDepartment of Mechanical Engineering, University of Maryland, College Park, MD 20742 USA.
S GuoDepartment of Electrical Engineering, Johns Hopkins University, Baltimore, MD 21211 USA.
N R SarfarazDepartment of Mechanical Engineering, University of Maryland, College Park, MD 20742 USA.
J U KangDepartment of Electrical Engineering, Johns Hopkins University, Baltimore, MD 21211 USA.
A KriegerDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, MD 21211 USA.
Johns Hopkins Medicine · USJohns Hopkins University · USUniversity of Maryland, College Park · US

Funding

Artificial intelligence Optical Coherence Tomography Guided Deep Anterior Lamellar Keratoplasty (AUTO-DALK)R01EY032127 · NEI · JOHNS HOPKINS UNIVERSITY · PI KANG, JIN U · 2021 to 2024
$1.6M
NEI NIH HHS R01 EY032127
6 · The paper itself

Abstract

This paper reports the design and evaluation of a novel piezo based actuator for needle drive in autonomous Deep Anterior Lamellar Keratoplasty (piezo-DALK). The actuator weighs less than 8g and is 20mm × 20mm × 10.5mm in size, making it ideal for eye-mounted applications. Mean open loop positional deviation was 1.17 ± 3.15um, and system repeatability and accuracy were 17.16um and 18.33um, respectively. Stall force was found to vary linearly with the cooling cycle and the actuator achieved a maximum drive force of 3.98N. When simulating the DALK procedure in synthetic corneal tissue, the piezo-DALK achieved a penetration depth of 643.56um which was equivalent to 92.1% of the total corneal thickness. This correlated closely with our desired depth of 90% ± 5% and took 2.5 hours to achieve. This work represents the first eye mountable actuator capable of "Big Bubble" needle drive for autonomous DALK procedures.

Indexed as

cornea transplantMedical robotsoptical coherence tomographyphase change materialpiezo-actuator

Identifiers

PMID38170110
PMCPMC10759147
OpenAlexW4200351864

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.