Evidence map›Paper›PMID 38168908›Full record

ReviewAmerican journal of obstetrics and gynecology2024

Pelvic floor injury during vaginal birth is life-altering and preventable: what can we do about it?

John O L DeLancey, Mariana Masteling, Fernanda Pipitone, Jennifer LaCross, Sara Mastrovito, James A Ashton-Miller

Registry-linked trialAbstract readReview
In one paragraph

Review in American journal of obstetrics and gynecology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07223736 (Postpartum Education Via Artificial Intelligence for Recovery and Loneliness), which is not on this map. Cited by 63 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07223736 narecruitingnot on this mapstarted 2026, after this paper: background citation

Postpartum Education Via Artificial Intelligence for Recovery and Loneliness (PEARL): A Randomized Controlled Trial

TypeinterventionalSponsorUniversity of California, San DiegoRan2026 to 2026Enrolled130ConditionsPelvic Floor Disorder, Loneliness, Postpartum, Mental HealthArmsGenerative artificial intelligence (genAI) postpartum chatbot, Standard of Care (SOC)
3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Additional benefits of pelvic floor proprioceptive training combined with conventional therapy in the treatment of female stress urinary incontinence.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Trial
  7. Trial
  8. Article
  9. Article
  10. Article
  11. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
    Review
  12. Female pelvic floor protection-Where do we have to go?Acta obstetricia et gynecologica Scandinavica · 2026
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Observational
  19. Diagnosis and management of urinary incontinence in females.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
    Review
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

John O L DeLanceyDepartment of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI. Electronic address: delancey@med.umich.edu.
Mariana MastelingDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, MI.
Fernanda PipitoneFaculty of Medicine, Hospital das Clinicas of the University of São Paulo, São Paulo, Brazil.
Jennifer LaCrossDepartment of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI.
Sara MastrovitoDepartment of Obstetrics and Gynecology, Fondazione Policlinico Universitario Agostino Gemelli, Rome, Italy.
James A Ashton-MillerDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, MI; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI.

Funding

Development of 21st Century Concepts and Tools for Quantifying Urethral Failure Mechanisms that Cause Urinary IncontinenceRC2DK122379 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ASHTON-MILLER, JAMES ANTHONY, DELANCEY, JOHN O.L. · 2019 to 2024
$5.7M
University of Michigan Kidney, Urology and Hematology Research Training NetworkU2CDK129445 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Subramaniam Pennathur · 2022 to 2026
$2.0M
NIDDK NIH HHS RC2 DK122379NIDDK NIH HHS U2C DK129445
6 · The paper itself

Abstract

Pelvic floor disorders after childbirth have distressing lifelong consequences for women, requiring more than 300,000 women to have surgery annually. This represents approximately 10% of the 3 million women who give birth vaginally each year. Vaginal birth is the largest modifiable risk factor for prolapse, the pelvic floor disorder most strongly associated with birth, and is an important contributor to stress incontinence. These disorders require 10 times as many operations as anal sphincter injuries. Imaging shows that injuries of the levator ani muscle, perineal body, and membrane occur in up to 19% of primiparous women. During birth, the levator muscle and birth canal tissues must stretch to more than 3 times their original length; it is this overstretching that is responsible for the muscle tear visible on imaging rather than compression or neuropathy. The injury is present in 55% of women with prolapse later in life, with an odds ratio of 7.3, compared with women with normal support. In addition, levator damage can affect other aspects of hiatal closure, such as the perineal body and membrane. These injuries are associated with an enlarged urogenital hiatus, now known as antedate prolapse, and with prolapse surgery failure. Risk factors for levator injury are multifactorial and include forceps delivery, occiput posterior birth, older maternal age, long second stage of labor, and birthweight of >4000 g. Delivery with a vacuum device is associated with reduced levator damage. Other steps that might logically reduce injuries include manual rotation from occiput posterior to occiput anterior, slow gradual delivery, perineal massage or compresses, and early induction of labor, but these require study to document protection. In addition, teaching women to avoid pushing against a contracted levator muscle would likely decrease injury risk by decreasing tension on the vulnerable muscle origin. Providing care for women who have experienced difficult deliveries can be enhanced with early recognition, physical therapy, and attention to recovery. It is only right that women be made aware of these risks during pregnancy. Educating women on the long-term pelvic floor sequelae of childbirth should be performed antenatally so that they can be empowered to make informed decisions about management decisions during labor.

Indexed as

Pelvic FloorPelvic Floor DisordersAnal CanalDelivery, ObstetricFemaleHumansPregnancyProlapseenlarged hiatusforceps deliverylevator ani avulsionocciput posteriorpelvic floor disorderspelvic floor injurypelvic organ prolapsepostpartum careprenatal educationpreventionrehabilitationstress urinary incontinencevaginal birth

Identifiers

PMID38168908
PMCPMC11177602

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.