ArticleNature plants2024
A conserved graft formation process in Norway spruce and Arabidopsis identifies the PAT gene family as central regulators of wound healing.
Article in Nature plants, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 21 citations in OpenAlex.
- Sticking together: a chitinase-like gene involved in cell wall remodeling is required for avocado graft compatibility.Plant physiology · 2026Article
- Molecular insights into avocado grafting: the role of chitinase-like genes.Plant physiology · 2026Article
- Dynamic characterization of graft union formation in Sapindus mukorossi: role of SmNDUFS4.Plant cell reports · 2026Article
- Integrated Transcriptome and Metabolome Analysis of Fruit Quality Variation in 'Sweet100' Tomato Across Different Growth Stages.Foods (Basel, Switzerland) · 2026Article
- Integrated multiomics analysis reveals the molecular mechanism of light intensity-enhanced healing in cotyledon-less splice grafted watermelon.Horticulture research · 2026Article
- A Statistical Mechanics Model to Decode Tissue Crosstalk During Graft Formation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- GhZAT11 triggers wound-activated bud growth by accelerating sugar transport and cell division.Nature plants · 2026Article
- The CiWOX13-CiWOX14 Complex RegulatesPlants (Basel, Switzerland) · 2026Article
- Graft compatibility emerges from the balance between regeneration and immunity: lessons from plant-plant interactions.Frontiers in plant science · 2026Review
- Identification and characterization of ninePlant signaling & behavior · 2025Article
- Article
- Drought Resistance Evaluation ofPlants (Basel, Switzerland) · 2025Article
- Genome-wide identification and functional analysis of the GRAS gene family in Medicago lupulina L.BMC genomics · 2025Article
- Wounding induces multilayered barrier formation in mature leaves via phytohormone signalling and ATML1-mediated epidermal specification.Nature plants · 2025Article
- Here comes the sun: integration of light, temperature, and auxin during herbaceous plant grafting.Planta · 2025Review
- Article
- Modern and historical uses of plant grafting to engineer development, stress tolerance, chimeras, and hybrids.The Plant journal : for cell and molecular biology · 2025Review
- Exogenous application of Eucommia ulmoides β-1, 4-glucanase promotes propagation by increasing the expression of wound healing genes.Scientific reports · 2024Article
- Advances in understanding the graft healing mechanism: a review of factors and regulatory pathways.Horticulture research · 2024Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
Abstract
The widespread use of plant grafting enables eudicots and gymnosperms to join with closely related species and grow as one. Gymnosperms have dominated forests for over 200 million years, and despite their economic and ecological relevance, we know little about how they graft. Here we developed a micrografting method in conifers using young tissues that allowed efficient grafting with closely related species and between distantly related genera. Conifer graft junctions rapidly connected vasculature and differentially expressed thousands of genes including auxin and cell-wall-related genes. By comparing these genes to those induced during Arabidopsis thaliana graft formation, we found a common activation of cambium, cell division, phloem and xylem-related genes. A gene regulatory network analysis in Norway spruce (Picea abies) predicted that PHYTOCHROME A SIGNAL TRANSDUCTION 1 (PAT1) acted as a core regulator of graft healing. This gene was strongly up-regulated during both spruce and Arabidopsis grafting, and Arabidopsis mutants lacking PAT genes failed to attach tissues or successfully graft. Complementing Arabidopsis PAT mutants with the spruce PAT1 homolog rescued tissue attachment and enhanced callus formation. Together, our data show an ability for young tissues to graft with distantly related species and identifies the PAT gene family as conserved regulators of graft healing and tissue regeneration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.