Evidence map›Paper›PMID 38168604›Full record

SynthesisAmerican journal of surgery2024

Subtotal vs total cholecystectomy for difficult gallbladders: A systematic review and meta-analysis.

Sylvia Sj Koo, Rohin J Krishnan, Kyle Ishikawa, Masako Matsunaga, Hyeong Jun Ahn, Kenric M Murayama, Riley K Kitamura

Open access · greenAbstract readSystematic ReviewMeta-AnalysisComparative Study
In one paragraph

Synthesis in American journal of surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sylvia Sj KooJohn A. Burns School of Medicine, University of Hawai'i, Honolulu, HI, 96813, USA; Department of Surgery, The Queen's Medical Center, Honolulu, HI, 96813, USA. Electronic address: Sylviask@hawaii.edu.
Rohin J KrishnanJohn A. Burns School of Medicine, University of Hawai'i, Honolulu, HI, 96813, USA.
Kyle IshikawaDepartment of Quantitative Health Sciences, University of Hawai'i, John A. Burns School of Medicine, Honolulu, HI, 96813, USA.
Masako MatsunagaDepartment of Quantitative Health Sciences, University of Hawai'i, John A. Burns School of Medicine, Honolulu, HI, 96813, USA.
Hyeong Jun AhnDepartment of Quantitative Health Sciences, University of Hawai'i, John A. Burns School of Medicine, Honolulu, HI, 96813, USA.
Kenric M MurayamaJohn A. Burns School of Medicine, University of Hawai'i, Honolulu, HI, 96813, USA; Department of Surgery, The Queen's Medical Center, Honolulu, HI, 96813, USA.
Riley K KitamuraJohn A. Burns School of Medicine, University of Hawai'i, Honolulu, HI, 96813, USA; Department of Surgery, The Queen's Medical Center, Honolulu, HI, 96813, USA.
University of Hawaiʻi at Mānoa · US

Funding

The Role of gp120 on Cardiovascular Disease in People Living with HIVU54MD007601 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI Benjamin C. Fogelgren · 2017 to 2026
$59.5M
Tracking and Evaluation CoreU54GM138062 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI SY, ANGELA U · 2021 to 2025
$15.5M
NIGMS NIH HHS U54 GM138062NIMHD NIH HHS U54 MD007601
6 · The paper itself

Abstract

introductionWith severely inflamed gallbladders, laparoscopic cholecystectomy can be difficult and may require procedures like subtotal cholecystectomy (SC). Few studies exist comparing SC and total cholecystectomy (TC) in the setting of severe biliary inflammation. This meta-analysis aims to compare SC and TC for difficult gallbladders.

methodsMedline-OVID, Embase-OVID, and Cinahl were searched including only studies comparing SC to TC for difficult gallbladders. Primary outcome was CBD injury. Secondary outcomes included bile leak, duodenal injury, retained stone, bleeding, intraabdominal collection, wound infection, reoperation, and mortality.

resultsTen studies were included. Compared to TC, SC significantly lowered the risk for CBD injury (0 ​% vs. 1.6 ​%, RR 0.30, 95%CI 0.10-0.87) but increased risk of bile leaks (RR 3.5, 95%CI 1.79-6.84), postoperative ERCP (RR 2.86, 95%CI 1.53-5.35), intraabdominal collections (RR 2.55, 95%CI 1.32-4.93), and reoperation (RR 2.92, 95%CI 1.14-7.47).

conclusionSC is a reasonable alternative to difficult gallbladders that may decrease the risk of CBD injuries. Knowing both approaches is crucial to manage the difficult gallbladder while minimizing harm. Further studies are needed to understand the value of SC for difficult cholecystectomy.

Indexed as

CholecystectomyCholecystectomy, LaparoscopicCholecystitisHumansPostoperative ComplicationsDifficult gallbladderSubtotal cholecystectomySystematic review and meta analysisTotal cholecystectomy

Identifiers

PMID38168604
PMCPMC11529787
OpenAlexW4389990307

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.