Evidence map›Paper›PMID 38168215›Full record

ArticleResearch square2023

Quantification of the flexural rigidity of endovascular surgical devices using three-point bending tests.

Michael Y Qiu, Charles B Suskin, Juan J Becerra-Garcia, Sophia H Roberts, DeVaughn G Rucker, Mohamed A Zayed, Joshua W Osbun, Guy M Genin

Abstract readPreprint
In one paragraph

Article in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michael Y QiuCardioVascular Research Innovation in Surgery & Engineering Center, Washington University in St. Louis, Missouri, USA.
Charles B SuskinCardioVascular Research Innovation in Surgery & Engineering Center, Washington University in St. Louis, Missouri, USA.
Juan J Becerra-GarciaCardioVascular Research Innovation in Surgery & Engineering Center, Washington University in St. Louis, Missouri, USA.
Sophia H RobertsCardioVascular Research Innovation in Surgery & Engineering Center, Washington University in St. Louis, Missouri, USA.
DeVaughn G RuckerCardioVascular Research Innovation in Surgery & Engineering Center, Washington University in St. Louis, Missouri, USA.
Mohamed A ZayedCardioVascular Research Innovation in Surgery & Engineering Center, Washington University in St. Louis, Missouri, USA.
Joshua W OsbunCardioVascular Research Innovation in Surgery & Engineering Center, Washington University in St. Louis, Missouri, USA.
Guy M GeninCardioVascular Research Innovation in Surgery & Engineering Center, Washington University in St. Louis, Missouri, USA.

Funding

Isovolumetric Multimodal Venous Thrombectomy SystemR42HL150963 · NHLBI · CAELI VASCULAR, LLC · PI LIEKWEG, STACEY, ZAYED, MOHAMED A. · 2021 to 2022
$2.0M
Cardiovascular Innovation Program in Surgery & EngineeringT32HL170959 · NHLBI · WASHINGTON UNIVERSITY · PI Guy M Genin, Eric CLAUDE Leuthardt · 2024 to 2026
$1.6M
Multi-Modal Venus Clot Removal DeviceR41HL150963 · NHLBI · CAELI VASCULAR, LLC · PI ZAYED, MOHAMED A. · 2020 to 2020
$194k
NHLBI NIH HHS R41 HL150963NHLBI NIH HHS R42 HL150963NHLBI NIH HHS T32 HL170959
6 · The paper itself

Abstract

Endovascular surgical procedures require the navigation of catheters and wires through the vasculature to reach distal target sites. Quantitative frameworks for device selection hold the potential to improve the tracking of endovascular devices through vascular anatomy by personalizing the device flexural rigidity to an individual's anatomy. However, data are lacking to facilitate this technology, in part because typical endovascular devices have intricate spatial variations in mechanical properties that are challenging and tedious to quantify repeatably. We therefore developed a three-point bend test methodology using a custom rig and applied it to measure lengthwise flexural rigidity profiles of endovascular devices that are used to target the cerebral vasculature. The methodology demonstrated high repeatability and was able to characterize transition zones. We applied the methodology to generate the first comprehensive, quantitative library of device flexural rigidities, spanning guidewires, intermediate guides, and long sheaths. We observed that these three classes of device have properties that fall into distinct ranges. Additional plots examining relationships between flexural rigidity, device diameter, and length revealed application-specific trends in flexural properties. This methodology and the data allow for standardized characterization and comparisons to aid device selection, and have the potential to both enhance surgical planning and inform future innovation.

Identifiers

PMID38168215
PMCPMC10760252

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.