ArticleNature communications2024
Prefrontal signals precede striatal signals for biased credit assignment in motivational learning biases.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Impaired midfrontal‑motor theta phase synchronization characterizes maladaptive motivational behavior in people with obsessive‑compulsive disorder.PLoS biology · 2026Article
- Long-term Learning Induces Plastic Changes in Frontostriatal Circuits.bioRxiv : the preprint server for biology · 2026Article
- Ultrasound neuromodulation reveals distinct roles of the dorsal anterior cingulate cortex and anterior insula in learning.PLoS biology · 2026Article
- Dopamine dynamics in human anterior cingulate cortex during Pavlovian-instrumental conflict.bioRxiv : the preprint server for biology · 2026Article
- Role of Prefrontal Cortex Circuitry in Maintaining Social Homeostasis.Biological psychiatry · 2025Review
- Decrease in decision noise from adolescence into adulthood mediates an increase in more sophisticated choice behaviors and performance gain.PLoS biology · 2024Article
- The unique role of anosognosia in the clinical progression of Alzheimer's disease: a disorder-network perspective.Communications biology · 2024Review
- Prefrontal signals precede striatal signals for biased credit assignment in motivational learning biases.Nature communications · 2024Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Actions are biased by the outcomes they can produce: Humans are more likely to show action under reward prospect, but hold back under punishment prospect. Such motivational biases derive not only from biased response selection, but also from biased learning: humans tend to attribute rewards to their own actions, but are reluctant to attribute punishments to having held back. The neural origin of these biases is unclear. Specifically, it remains open whether motivational biases arise primarily from the architecture of subcortical regions or also reflect cortical influences, the latter being typically associated with increased behavioral flexibility and control beyond stereotyped behaviors. Simultaneous EEG-fMRI allowed us to track which regions encoded biased prediction errors in which order. Biased prediction errors occurred in cortical regions (dorsal anterior and posterior cingulate cortices) before subcortical regions (striatum). These results highlight that biased learning is not a mere feature of the basal ganglia, but arises through prefrontal cortical contributions, revealing motivational biases to be a potentially flexible, sophisticated mechanism.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.