Evidence map›Paper›PMID 38167988›Full record

ArticleScientific reports2024

Evaluation of the reliability and readability of ChatGPT-4 responses regarding hypothyroidism during pregnancy.

C E Onder, G Koc, P Gokbulut, I Taskaldiran, S M Kuskonmaz

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
12.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 106 citations in OpenAlex.

  1. Article
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  3. Assessment of ChatGPT's Performance on the ACP 2024 National Prosthodontics Resident Exam (NPRE).European journal of dental education : official journal of the Association for Dental Education in Europe · 2026
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  10. Artificial intelligence in obstetrics and gynecology: Evaluating ChatGPT and Google Gemini in answering patient questions.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Article
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

C E OnderDepartment of Endocrinology and Metabolic Diseases, Ankara Training and Research Hospital, Ankara, Turkey. drcagatayonder@gmail.com.ORCID 0000-0002-0293-2309
G KocDepartment of Endocrinology and Metabolic Diseases, Ankara Training and Research Hospital, Ankara, Turkey.ORCID 0000-0002-8512-4816
P GokbulutDepartment of Endocrinology and Metabolic Diseases, Ankara Training and Research Hospital, Ankara, Turkey.ORCID 0000-0002-6287-7655
I TaskaldiranDepartment of Endocrinology and Metabolic Diseases, Ankara Training and Research Hospital, Ankara, Turkey.ORCID 0000-0002-1390-7571
S M KuskonmazDepartment of Endocrinology and Metabolic Diseases, Ankara Training and Research Hospital, Ankara, Turkey.ORCID 0000-0002-2602-1657
Ministry of Health · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypothyroidism is characterized by thyroid hormone deficiency and has adverse effects on both pregnancy and fetal health. Chat Generative Pre-trained Transformer (ChatGPT) is a large language model trained with a very large database from many sources. Our study was aimed to evaluate the reliability and readability of ChatGPT-4 answers about hypothyroidism in pregnancy. A total of 19 questions were created in line with the recommendations in the latest guideline of the American Thyroid Association (ATA) on hypothyroidism in pregnancy and were asked to ChatGPT-4. The reliability and quality of the responses were scored by two independent researchers using the global quality scale (GQS) and modified DISCERN tools. The readability of ChatGPT was assessed used Flesch Reading Ease (FRE) Score, Flesch-Kincaid grade level (FKGL), Gunning Fog Index (GFI), Coleman-Liau Index (CLI), and Simple Measure of Gobbledygook (SMOG) tools. No misleading information was found in any of the answers. The mean mDISCERN score of the responses was 30.26 ± 3.14; the median GQS score was 4 (2-4). In terms of reliability, most of the answers showed moderate (78.9%) followed by good (21.1%) reliability. In the readability analysis, the median FRE was 32.20 (13.00-37.10). The years of education required to read the answers were mostly found at the university level [9 (47.3%)]. Although ChatGPT-4 has significant potential, it can be used as an auxiliary information source for counseling by creating a bridge between patients and clinicians about hypothyroidism in pregnancy. Efforts should be made to improve the reliability and readability of ChatGPT.

Indexed as

Health LiteracyHypothyroidismCholine O-AcetyltransferaseComprehensionFemaleHumansInternetPregnancyReadingReproducibility of ResultsUnited StatesCholine O-Acetyltransferase

Identifiers

PMID38167988
PMCPMC10761760
OpenAlexW4390498094

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.