Evidence map›Paper›PMID 38167987›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2024

Differences in PPD- and mitogen-induced T-cell activation marker expression characterize immunopathology in acute tuberculosis patients.

Isaac Acheampong, Difery Minadzi, Edwin F Laing, Michael Frimpong, Monika M Vivekanandan, Augustine Yeboah, Ernest Adankwah, Wilfred Aniagyei, Joseph F Arthur, Millicent Lamptey and 11 more

Open access · hybridAbstract read
In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Correlation Between CD38Diabetes, metabolic syndrome and obesity : targets and therapy · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 6 institutions in 2 countries.

Isaac AcheampongKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Difery MinadziKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Edwin F LaingSchool of Medicine and Dentistry, College of Health Sciences, Kwame Nkrumah University of Science and Technology KNUST, Kumasi, Ghana.
Michael FrimpongSchool of Medicine and Dentistry, College of Health Sciences, Kwame Nkrumah University of Science and Technology KNUST, Kumasi, Ghana.
Monika M VivekanandanKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Augustine YeboahKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Ernest AdankwahKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Wilfred AniagyeiKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Joseph F ArthurKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Millicent LampteyKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Mohammed K AbassAgogo Presbyterian Hospital, Agogo, Ghana.
Francis KumbelSt. Mathias Catholic Hospital, Yeji, Ghana.
Francis Osei-YeboahAtebubu District Hospital, Atebubu, Ghana.
Amidu GawusuSene West Health Directorate, Kwame Danso, Ghana.
Linda Batsa DebrahKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Dorcas O OwusuKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Alexander DebrahKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Ertan MayatepekDepartment of General Pediatrics, Neonatology and Pediatric Cardiology, Medical Faculty, University Hospital Duesseldorf, Heinrich-Heine-University, 40225, Duesseldorf, Germany.
Julia SeyfarthDepartment of General Pediatrics, Neonatology and Pediatric Cardiology, Medical Faculty, University Hospital Duesseldorf, Heinrich-Heine-University, 40225, Duesseldorf, Germany.
Richard O PhillipsKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Marc JacobsenDepartment of General Pediatrics, Neonatology and Pediatric Cardiology, Medical Faculty, University Hospital Duesseldorf, Heinrich-Heine-University, 40225, Duesseldorf, Germany. marc.jacobsen@med.uni-duesseldorf.de.ORCID http://orcid.org/0000-0002-4703-5652
Kumasi Centre for Collaborative Research in Tropical Medicine · GHKwame Nkrumah University of Science and Technology · GHDüsseldorf University Hospital · DECatholic University College of Ghana · GHGhana Health Service · GHPresbyterian University, Ghana · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Impaired T-cell responses to mitogens and high T-cell activation marker (TAM) expression on Mycobacterium tuberculosis-specific T-cells characterize immunopathology in patients with tuberculosis (TB). In a study of patients with TB (n = 60) and asymptomatic contacts (controls, n = 37), we found that TB patients had higher CD38

Indexed as

Mycobacterium tuberculosisTuberculosisAntigens, BacterialHumansMitogensT-LymphocytesTuberculinAntigens, BacterialMitogensTuberculinAnergyImmunopathologyMitogenT-cell activation markerTuberculosis

Identifiers

PMID38167987
PMCPMC10917863
OpenAlexW4390521479

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.