ArticleNature communications2024
Dual-wavelength metalens enables Epi-fluorescence detection from single molecules.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Article
- Article
- Metalens-style image synthesis for metalens imaging via image-to-image translation.Scientific reports · 2026Article
- Production-Ready Double-Sided Fabrication of Dual-Band Infrared Metaoptics Using Deep-Ultraviolet Lithography.ACS nano · 2025Article
- Image scanning microscopy based on multifocal metalens for sub-diffraction-limited imaging of brain organoids.Light, science & applications · 2025Article
- Inverse Design of Multi-Wavelength Achromatic Metalens Integrated On-Chip with Planar Waveguide.Nanomaterials (Basel, Switzerland) · 2025Article
- The Principle and Application of Achromatic Metalens.Micromachines · 2025Review
- Broadband achromatic metalens for high-resolution imaging.Light, science & applications · 2025Article
- Axially multifocal metalens for 3D volumetric photoacoustic imaging of neuromelanin in live brain organoid.Science advances · 2025Article
- Dual-Wavelength On-Chip Integrated Metalens for Epi-Fluorescence Single-Molecule Sensing.Sensors (Basel, Switzerland) · 2024Article
- Multiple Multicolored 3D Polarization Knots Arranged along Light Propagation.ACS photonics · 2024Article
- Electrically tunable planar liquid-crystal singlets for simultaneous spectrometry and imaging.Light, science & applications · 2024Article
- Multiwavelength Achromatic Deflector in the Visible Using a Single-Layer Freeform Metasurface.Nano letters · 2024Article
- Multifaceted control of focal points along an arbitrary 3D curved trajectory.Light, science & applications · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Single molecule fluorescence spectroscopy is at the heart of molecular biophysics research and the most sensitive biosensing assays. The growing demand for precision medicine and environmental monitoring requires the creation of miniaturized and portable sensing platforms. However, the need for highly sophisticated objective lenses has precluded the development of single molecule detection systems for truly portable devices. Here, we propose a dielectric metalens device of submicrometer thickness to excite and collect light from fluorescent molecules instead of an objective lens. The high numerical aperture, high focusing efficiency, and dual-wavelength operation of the metalens enable the implementation of fluorescence correlation spectroscopy with a single Alexa 647 molecule in the focal volume. Moreover, the metalens enables real-time monitoring of individual fluorescent nanoparticle transitions and identification of hydrodynamic diameters ranging from a few to hundreds of nanometers. This advancement in sensitivity extends the application of the metalens technology to ultracompact single-molecule sensors.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.