Evidence map›Paper›PMID 38167790›Full record

ArticleNature communications2024

Selective blockade of Ca

Pietro Mesirca, Jean Chemin, Christian Barrère, Eleonora Torre, Laura Gallot, Arnaud Monteil, Isabelle Bidaud, Sylvie Diochot, Michel Lazdunski, Tuck Wah Soong and 3 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Impact of CaInternational journal of molecular sciences · 2026
    Review
  3. L-Type CaCirculation research · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Aging and sinus node dysfunction: mechanisms and future directions.Clinical science (London, England : 1979) · 2025
    Review
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 3 countries.

Pietro MesircaInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, 34094, Montpellier, France. pietro.mesirca@igf.cnrs.fr.ORCID 0000-0002-9538-3096
Jean Chemin *Institut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, 34094, Montpellier, France.
Christian Barrère *Institut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, 34094, Montpellier, France.
Eleonora TorreInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, 34094, Montpellier, France.
Laura GallotInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, 34094, Montpellier, France.
Arnaud MonteilInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, 34094, Montpellier, France.ORCID 0000-0003-1632-7318
Isabelle BidaudInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, 34094, Montpellier, France.
Sylvie DiochotLaboratory of Excellence Ion Channels, Science & Therapeutics, F-06560, Valbonne, France.
Michel LazdunskiLaboratory of Excellence Ion Channels, Science & Therapeutics, F-06560, Valbonne, France.
Tuck Wah SoongDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.ORCID 0000-0002-0876-0325
Stéphanie Barrère-LemaireInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, 34094, Montpellier, France.
Matteo E MangoniInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, 34094, Montpellier, France.ORCID 0000-0002-8892-3373
Joël NargeotInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, 34094, Montpellier, France. joel.nargeot@igf.cnrs.fr.ORCID 0000-0003-2893-5636
Centre National de la Recherche Scientifique · FRNational University of Singapore · SG

Funding

Fondation Leducq 19CV03
6 · The paper itself

Abstract

L-type voltage-gated calcium channels are involved in multiple physiological functions. Currently available antagonists do not discriminate between L-type channel isoforms. Importantly, no selective blocker is available to dissect the role of L-type isoforms Ca

Indexed as

Calcium Channels, L-TypeDendroaspisAnimalsCalciumElapid VenomsMyocytes, CardiacProtein IsoformscalciseptineCalciumCalcium Channels, L-TypeElapid VenomsProtein Isoforms

Identifiers

PMID38167790
PMCPMC10762068
OpenAlexW4390500080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.