Evidence map›Paper›PMID 38167486›Full record

ArticleNature communications2024

Cultured meat with enriched organoleptic properties by regulating cell differentiation.

Milae Lee, Sohyeon Park, Bumgyu Choi, Woojin Choi, Hyun Lee, Jeong Min Lee, Seung Tae Lee, Ki Hyun Yoo, Dongoh Han, Geul Bang and 4 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
33.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 99 citations in OpenAlex.

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  12. Integrative Adipogenic Engineering of Cultured Fat for Cell Based Meat.Comprehensive reviews in food science and food safety · 2026
    Review
  13. Probiotic-Based Materials as Living Therapeutics.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  14. Review
  15. Bioprocess Engineering for Cultivated Meat.Advances in biochemical engineering/biotechnology · 2026
    Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Milae LeeDepartment of Chemical & Biomolecular Engineering, College of Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.ORCID 0000-0003-0569-0365
Sohyeon ParkDepartment of Chemical & Biomolecular Engineering, College of Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
Bumgyu ChoiDepartment of Chemical & Biomolecular Engineering, College of Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
Woojin ChoiDepartment of Chemical & Biomolecular Engineering, College of Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.ORCID 0000-0002-5886-8836
Hyun LeeDepartment of Animal Life Science, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon-si, Gangwon-do, 24341, Republic of Korea.
Jeong Min LeeDepartment of Applied Animal Life Science, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon-si, Gangwon-do, 24341, Republic of Korea.ORCID 0000-0002-1894-0629
Seung Tae LeeDepartment of Animal Life Science, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon-si, Gangwon-do, 24341, Republic of Korea.
Ki Hyun YooSimple Planet, 805, 34, sangwan 12-gil, Seongdong-gu, Seoul, 04790, Republic of Korea.ORCID 0000-0003-1088-3540
Dongoh HanSimple Planet, 805, 34, sangwan 12-gil, Seongdong-gu, Seoul, 04790, Republic of Korea.ORCID 0009-0007-9157-6994
Geul BangResearch Center for Bioconvergence Analysis, Korea Basic Science Institute, Cheongju, 28119, Republic of Korea.ORCID 0000-0002-8762-9877
Heeyoun HwangResearch Center for Bioconvergence Analysis, Korea Basic Science Institute, Cheongju, 28119, Republic of Korea.ORCID 0000-0002-0124-2533
Won-Gun KohDepartment of Chemical & Biomolecular Engineering, College of Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
Sangmin LeeSchool of Mechanical Engineering, Chung-ang University, 84, Heukseok-ro, Dongjak-gu, Seoul, 06974, Republic of Korea. slee98@cau.ac.kr.ORCID 0000-0002-6713-4797
Jinkee HongDepartment of Chemical & Biomolecular Engineering, College of Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea. jinkee.hong@yonsei.ac.kr.ORCID 0000-0003-3243-8536
Yonsei University · KRKangwon National University · KRKorea Basic Science Institute · KR

Funding

Ministry of National Defense, Republic of Korea | Defense Acquisition Program Administration (DAPA) KRIT-CT-21-034Ministry of Trade, Industry and Energy (Ministry of Trade, Industry and Energy, Korea) 20012384National Research Foundation of Korea (NRF) 2019M3A9H110378622National Research Foundation of Korea (NRF) 2021R1A4A3030268
6 · The paper itself

Abstract

Research on cultured meat has primarily focused on the mass proliferation or differentiation of muscle cells; thus, the food characteristics of cultured meat remain relatively underexplored. As the quality of meat is determined by its organoleptic properties, cultured meat with similar sensory characteristics to animal-derived meat is highly desirable. In this study, we control the organoleptic and nutritional properties of cultured meat by tailoring the 2D differentiation of primary bovine myoblasts and primary bovine adipose-derived mesenchymal stem cells on gelatin/alginate scaffolds with varying stiffness. We assess the effect of muscle and adipose differentiation quality on the sensory properties of cultured meat. Thereafter, we fabricate cultured meat with similar sensory profiles to that of conventional beef by assembling the muscle and adipose constructs composed of highly differentiated cells. We introduce a strategy to produce cultured meat with enriched food characteristics by regulating cell differentiation with scaffold engineering.

Indexed as

Mesenchymal Stem CellsTissue ScaffoldsAnimalsCattleCell DifferentiationCells, CulturedIn Vitro Meat

Identifiers

PMID38167486
PMCPMC10762223
OpenAlexW4390509116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.