ArticleScientific reports2024
Association between sarcopenia and osteoarthritis among the US adults: a cross-sectional study.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 29 citations in OpenAlex.
- Association of possible sarcopenia, sarcopenia and knee osteoarthritis among middle-aged and older adults: Evidence from the CHARLS cohort.Clinics (Sao Paulo, Brazil) · 2026Article
- Heat-TreatedCells · 2026Article
- Association between the sarcopenia index and osteoarthritis: a cross-sectional and longitudinal study.European journal of medical research · 2026Article
- Osteoarthritis as a systemic disorder: multi-organ crosstalk in pathogenesis and therapeutic targeting.Frontiers in immunology · 2026Review
- Joint trajectories of frailty and depressive symptoms and risk of incident osteoarthritis in middle-aged and older adults.Frontiers in public health · 2026Article
- Associations Between Longitudinal Changes in Frailty and Incident Arthritis: A Multi-Cohort Study.Risk management and healthcare policy · 2026Article
- Creatinine, leucine, and tetrahydrocorticosterone emerge as potential biomarkers for the diagnosis of sarcopenic osteoarthritis in middle-aged and elderly individuals: a cross-sectional exploratory study.Frontiers in molecular biosciences · 2026Article
- Sarcopenia severity and its prognostic value for structural and functional progression in elderly patients with knee osteoarthritis: a 24-month retrospective cohort study.American journal of translational research · 2026Article
- Higher Prevalence of Sarcopenia in Knee Osteoarthritis and Its Association with Femoral Intercondylar Cartilage Thickness and Functional Outcomes.Life (Basel, Switzerland) · 2025Article
- Development and validation of the BPDKC model for predicting sarcopenic knee osteoarthritis in community-dwelling older adults: a cross-sectional study.BMC musculoskeletal disorders · 2025Article
- Research progress on sarcopenia in the musculoskeletal system.Bone research · 2025Review
- Improved Strength Prediction Combining MRI Biomarkers of Muscle Quantity and Quality.NMR in biomedicine · 2025Article
- Identification of shared key genes and pathways in osteoarthritis and sarcopenia patients based on bioinformatics analysis.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Article
- Association between neutrophil percentage-to-albumin ratio (NPAR) and sarcopenia in individuals with arthritis: a cross-sectional study.Frontiers in medicine · 2025Article
- Association between visceral adiposity index and osteoarthritis in U.S. adults aged 50 and older: a cross-sectional study.Frontiers in nutrition · 2025Article
- Muscle quality index correlates with arthritis: a cross-sectional study from NHANES 2011-2014.Frontiers in medicine · 2025Article
- Association between serum C-reactive protein and low muscle mass among US adults: Results from NHANES 1999 to 2006.Clinics (Sao Paulo, Brazil) · 2025Article
- #NoDaysOff: examining the relationship between exercise habits and lifestyle-based consumer behavior.Frontiers in psychology · 2025Article
- Kashin-Beck Disease: A Risk Factor for Sarcopenia and Its Interaction with Selenium.Nutrients · 2024Article
- Association of sarcopenia and its prognostic value in symptomatic knee osteoarthritis among older people in China: the first longitudinal evidence from CHARLS.BMC geriatrics · 2024Article
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
The association between sarcopenia and OA still presents many uncertainties. We aimed to assess whether sarcopenia is associated with occurrence of OA in US adults. We conducted a cross-sectional study consisting of 11,456 participants from National Health and Nutrition Examination Survey 1999-2006. Sarcopenia was defined by a low muscle mass. The skeletal muscle index (SMI) was calculated as the appendicular skeletal muscle mass divided by body mass indexes (BMI) or body weight. OA status was assessed by using self-reported questionnaire. We evaluated the association between sarcopenia and OA using multivariate regression models. In addition, subgroup and interaction analysis were performed. Sarcopenia was associated with OA when it was defined by the BMI-adjusted SMI (OR = 1.23 [95% CI, 1.01, 1.51]; P = 0.038) and defined by the weight-adjusted SMI (OR = 1.30 [95% CI, 1.10, 1.55]; P = 0.003). Subgroup and interaction analysis found that the strongest positive association mainly exists in smoker (OR = 1.54 [95% CI, 1.21, 1.95], Pint = 0.006), and this association is not significant in other groups. In conclusion, we found that sarcopenia was associated with occurrence of OA. Subgroup analysis revealed that the association between sarcopenia and OA was more pronounced in smoker. Further well-designed prospective cohort studies are needed to assess our results.
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