Evidence map›Paper›PMID 38167434›Full record

ArticleScientific reports2024

Home-based monitoring of persons with advanced Parkinson's disease using smartwatch-smartphone technology.

Tsviya Fay-Karmon, Noam Galor, Benedetta Heimler, Asaf Zilka, Ronny P Bartsch, Meir Plotnik, Sharon Hassin-Baer

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  8. Digital Technologies for Symptom Monitoring in Parkinson Disease.Current neurology and neuroscience reports · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tsviya Fay-KarmonMovement Disorders Institute, Department of Neurology, Sheba Medical Center, Ramat Gan, Israel.
Noam GalorCenter of Advanced Technologies in Rehabilitation, Sheba Medical Center, Ramat Gan, Israel.
Benedetta HeimlerCenter of Advanced Technologies in Rehabilitation, Sheba Medical Center, Ramat Gan, Israel.
Asaf ZilkaMovement Disorders Institute, Department of Neurology, Sheba Medical Center, Ramat Gan, Israel.
Ronny P BartschDepartment of Physics, Bar-Ilan University, Ramat Gan, Israel.
Meir PlotnikCenter of Advanced Technologies in Rehabilitation, Sheba Medical Center, Ramat Gan, Israel.
Sharon Hassin-BaerMovement Disorders Institute, Department of Neurology, Sheba Medical Center, Ramat Gan, Israel. sharon.hassin@sheba.health.gov.il.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Movement deterioration is the hallmark of Parkinson's disease (PD), characterized by levodopa-induced motor-fluctuations (i.e., symptoms' variability related to the medication cycle) in advanced stages. However, motor symptoms are typically too sporadically and/or subjectively assessed, ultimately preventing the effective monitoring of their progression, and thus leading to suboptimal treatment/therapeutic choices. Smartwatches (SW) enable a quantitative-oriented approach to motor-symptoms evaluation, namely home-based monitoring (HBM) using an embedded inertial measurement unit. Studies validated such approach against in-clinic evaluations. In this work, we aimed at delineating personalized motor-fluctuations' profiles, thus capturing individual differences. 21 advanced PD patients with motor fluctuations were monitored for 2 weeks using a SW and a smartphone-dedicated app (Intel Pharma Analytics Platform). The SW continuously collected passive data (tremor, dyskinesia, level of activity using dedicated algorithms) and active data, i.e., time-up-and-go, finger tapping, hand tremor and hand rotation carried out daily, once in OFF and once in ON levodopa periods. We observed overall high compliance with the protocol. Furthermore, we observed striking differences among the individual patterns of symptoms' levodopa-related variations across the HBM, allowing to divide our participants among four data-driven, motor-fluctuations' profiles. This highlights the potential of HBM using SW technology for revolutionizing clinical practices.

Indexed as

LevodopaParkinson DiseaseAntiparkinson AgentsHumansSmartphoneTremorAntiparkinson AgentsLevodopa

Identifiers

PMID38167434
PMCPMC10761812

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.