ArticleNature communications2024
Atomic-resolution structure analysis inside an adaptable porous framework.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 21 citations in OpenAlex.
- Two novel compounds (lovastatin analog Y and lovastatin analog Z) isolated from health foods containing beni-koji (red yeast rice) with adverse events report.Journal of natural medicines · 2026Article
- An Adaptable Porous Metal-Organic Framework for Structural Visualization of Beyond Rule of 5 Molecules on the Microgram Scale.Journal of the American Chemical Society · 2026Article
- Second-Generation Crystalline Sponges Enabling Consistent Structure Analysis Under Standardized Conditions for Diverse Molecules.Angewandte Chemie (International ed. in English) · 2026Article
- Discovery of Coracanols A and B, Two Biological Nitrification Inhibition Diterpenoids from Finger Millet.Organic letters · 2026Article
- Automated Nanocrystalline Sponge Workflow Enabled by 3D Electron Diffraction.Journal of the American Chemical Society · 2026Article
- Supramolecular Chemistry in Metal-Organic Framework Materials.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Structural Elucidation of Nucleophilic Compounds through Synergistic Coordination and Hydrogen Bonding in a Metal-Organic Framework.Journal of the American Chemical Society · 2025Article
- Supramolecular coordination cages as crystalline sponges through a symmetry mismatch strategy.Nature chemistry · 2025Article
- Statistical optimization of guest uptake in crystalline sponges: grading structural outcomes.IUCrJ · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
We introduce a versatile metal-organic framework (MOF) for encapsulation and immobilization of various guests using highly ordered internal water network. The unique water-mediated entrapment mechanism is applied for structural elucidation of 14 bioactive compounds, including 3 natural product intermediates whose 3D structures are clarified. The single-crystal X-ray diffraction analysis reveals that incorporated guests are surrounded by hydrogen-bonded water networks inside the pores, which uniquely adapt to each molecule, providing clearly defined crystallographic sites. The calculations of host-solvent-guest structures show that the guests are primarily interacting with the MOF through weak dispersion forces. In contrast, the coordination and hydrogen bonds contribute less to the total stabilization energy, however, they provide highly directional point interactions, which help align the guests inside the pore.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.